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QuickView for MG44;jsessionid=5468E4B4100A40B22F5FBBC9E3AA5518;jsessionid=335B7C0C356830470477CAE00515F5B0 (gene)


Gene Symbol:
Suv39h1 Mus musculus Mus musculus
Full name:
suppressor of variegation 3-9 1
Synonyms:
AI852103, AL022883, DXHXS7466e, H3-K9-HMTase 1, KMT1A, mIS6, histone-lysine N-methyltransferase SUV39H1, Suv39h histone methyltransferase, histone H3-K9 methyltransferase 1, position-effect variegation 3-9 homolog, su(var)3-9 homolog 1, suppressor of variegation 3-9 homolog 1
Genomic Location:
Chr X: 7638430-7651712
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | histone-lysine N-methyltransferase activity | lysine N-methyltransferase activity | protein methyltransferase activity | cation binding | nucleic acid binding | S-adenosylmethionine-dependent methyltransferase activity | catalytic activity | protein N-terminus binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | histone methyltransferase activity (H3-K9 specific) | histone methyltransferase activity | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | double-stranded DNA binding | N-methyltransferase activity | RNA polymerase II regulatory region sequence-specific DNA binding | transferase activity | transition metal ion binding | protein-lysine N-methyltransferase activity | methyltransferase activity | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | cellular response to decreased oxygen levels | RNA processing | peptidyl-amino acid modification | negative regulation of cellular process | negative regulation of RNA biosynthetic process | histone modification | cell differentiation | histone-lysine N-methyltransferase activity | lysine N-methyltransferase activity | protein methyltransferase activity | cellular process | regulation of gene expression, epigenetic | chromatin organization | negative regulation of nucleic acid-templated transcription | response to hypoxia | ribosome biogenesis | negative regulation of cellular metabolic process | regulation of cellular process | gene silencing | regulation of metabolic process | S-adenosylmethionine-dependent methyltransferase activity | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | cellular response to hypoxia | histone H3-K9 dimethylation | response to stress | negative regulation of circadian rhythm | cellular nitrogen compound biosynthetic process | ncRNA processing | rhythmic process | cellular nitrogen compound metabolic process | peptidyl-lysine trimethylation | negative regulation of metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | regulation of nucleic acid-templated transcription | response to oxygen levels | nitrogen compound metabolic process | histone methylation | cellular response to DNA damage stimulus | regulation of gene expression | methylation | cellular response to stress | cell cycle | negative regulation of gene expression, epigenetic | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | histone methyltransferase activity (H3-K9 specific) | histone H3-K9 trimethylation | biosynthetic process | histone H3-K9 methylation | aromatic compound biosynthetic process | histone methyltransferase activity | peptidyl-lysine dimethylation | rRNA metabolic process | regulation of cellular metabolic process | regulation of RNA metabolic process | rRNA processing | protein metabolic process | peptidyl-lysine methylation | N-methyltransferase activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | peptidyl-lysine modification | nucleobase-containing compound metabolic process | organic substance metabolic process | histone lysine methylation | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | chromatin silencing at rDNA | DNA packaging | transcription, DNA-templated | covalent chromatin modification | regulation of transcription, DNA-templated | protein-lysine N-methyltransferase activity | histone H3-K9 modification | cellular protein metabolic process | cellular macromolecule biosynthetic process | protein methylation | regulation of circadian rhythm | methyltransferase activity | developmental process | organelle organization | cellular protein modification process | negative regulation of transcription by RNA polymerase II | ncRNA metabolic process | DNA conformation change | heterocycle metabolic process | chromosome organization | chromatin silencing | ribonucleoprotein complex biogenesis | cellular metabolic process | macromolecule metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | rDNA heterochromatin | chromosome, centromeric region | cell | nuclear lumen | nuclear transcriptional repressor complex | intracellular organelle | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | transcriptional repressor complex | heterochromatin | nucleus | organelle | nuclear heterochromatin | membrane-enclosed lumen | nuclear chromatin | chromatin silencing complex | intracellular