QuickView for MST1;jsessionid=C660C586B29751A003273B2D277611F3;jsessionid=02B2B1BAD62A10ACF5E6AE473986E318;jsessionid=C84FABFE9B2CC58D2664360E9BB06D0A (gene)

Gene Symbol:

MST1 Homo sapiens

Full name:

macrophage stimulating 1

Synonyms:

D3F15S2, DNF15S2, HGFL, MSP, NF15S2, hepatocyte growth factor-like protein, hepatocyte growth factor-like protein homolog, macrophage stimulating 1 (hepatocyte growth factor-like), macrophage-stimulating protein

Genomic Location:

Chr 3: 49696391-49701099

Description:

The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary mot...

View Full Description

The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

VDR_Q6 ,  GATAAGR_GATA_C ,  GATA1_04 ,  GGGCGGR_SP1_Q6 ,  AHR_Q5 ,  NRF1_Q6 ,  YGCGYRCGC_UNKNOWN ,  SREBP_Q3 ,  CTGCAGY_UNKNOWN ,  RCGCANGCGY_NRF1_Q6

Cytogenetic Map:

3p21.31

search → result