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QuickView for MSTN;jsessionid=E9CCEBBE2AA7BD8E1BB3A3343B1AAF7B;jsessionid=0DC0CC130B9EC95B9ADBF9762011B159;jsessionid=1D7483102E0641E56DCC09801543AFA7 (gene)


Gene Symbol:
MSTN Gallus gallus Gallus gallus
Full name:
myostatin
Synonyms:
GDF8
Genomic Location:
Chr 7: 199294-204786
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Canis lupus familiaris Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001001461
Protein Names
O42220
Q53YW8
Q98SP0
Q06BS3



GO Molecular Function

transforming growth factor beta receptor binding | signaling receptor binding | carbohydrate derivative binding | cytokine receptor binding | molecular function regulator | anion binding | identical protein binding | ion binding | heparin binding | protein binding | protein homodimerization activity | receptor regulator activity | protein dimerization activity | growth factor activity | receptor ligand activity | cytokine activity | glycosaminoglycan binding

GO Biological Process

negative regulation of phosphorylation | SMAD protein signal transduction | negative regulation of cellular response to insulin stimulus | negative regulation of skeletal muscle tissue growth | positive regulation of macromolecule biosynthetic process | muscle tissue development | regulation of programmed cell death | negative regulation of skeletal muscle satellite cell proliferation | response to hormone | negative regulation of cellular process | negative regulation of kinase activity | response to dexamethasone | cell differentiation | negative regulation of satellite cell differentiation | response to drug | positive regulation of phosphate metabolic process | regulation of skeletal muscle cell differentiation | positive regulation of cellular biosynthetic process | cellular process | negative regulation of muscle organ development | cellular homeostasis | negative regulation of signaling | negative regulation of developmental growth | positive regulation of pathway-restricted SMAD protein phosphorylation | regulation of skeletal muscle cell proliferation | regulation of striated muscle tissue development | response to growth factor | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | muscle structure development | anatomical structure homeostasis | skeletal muscle organ development | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | regulation of skeletal muscle satellite cell proliferation | positive regulation of cellular protein metabolic process | response to transforming growth factor beta | response to stimulus | positive regulation of protein metabolic process | cellular response to xenobiotic stimulus | regulation of skeletal muscle tissue growth | skeletal muscle tissue development | regulation of cell proliferation | cellular response to organic cyclic compound | negative regulation of muscle tissue development | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | embryo development | molecular function regulator | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | regulation of skeletal muscle tissue development | system development | regulation of signal transduction | negative regulation of growth | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of MAPK cascade | regulation of catalytic activity | regulation of phosphorylation | regulation of gene expression | response to ketone | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | negative regulation of insulin receptor signaling pathway | response to corticosteroid | negative regulation of myoblast differentiation | cell proliferation | negative regulation of protein kinase B signaling | regulation of cellular protein metabolic process | muscle cell cellular homeostasis | cellular response to glucocorticoid stimulus | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | cellular response to drug | striated muscle tissue development | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | negative regulation of striated muscle tissue development | homeostatic process | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | negative regulation of skeletal muscle cell differentiation | cellular response to transforming growth factor beta stimulus | negative regulation of myoblast proliferation | regulation of signaling receptor activity | receptor regulator activity | positive regulation of protein modification process | regulation of growth | response to organic substance | regulation of kinase activity | response to antineoplastic agent | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | growth factor activity | regulation of RNA biosynthetic process | regulation of myoblast differentiation | regulation of myoblast proliferation | negative regulation of skeletal muscle tissue development | receptor ligand activity | cytokine activity | animal organ development | regulation of insulin receptor signaling pathway | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | cellular response to steroid hormone stimulus | cellular response to dexamethasone stimulus | transforming growth factor beta receptor signaling pathway | regulation of cell communication | negative regulation of molecular function | muscle cell proliferation | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cell development | regulation of developmental growth | positive regulation of phosphorylation | regulation of developmental process | developmental process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of metabolic process | cellular response to organic substance | regulation of cell death | response to steroid hormone | negative regulation of cell differentiation | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | regulation of pathway-restricted SMAD protein phosphorylation | positive regulation of gene expression | response to glucocorticoid | cellular response to growth factor stimulus | regulation of muscle organ development | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

cell | extracellular region | extracellular space