QuickView for MTHFR;jsessionid=1F655A875013ED8613E73E8091FD15D7;jsessionid=75E157BB36221DBAF33DE912F79B2DD8 (gene)
- Gene Symbol:
- MET13
Saccharomyces cerevisiae - Full name:
- Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
- Synonyms:
- MET11, MET13, YGL125W
- Genomic Location:
- Chr VII: 272526-274328
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | methylenetetrahydrofolate reductase (NAD(P)H) activity | oxidoreductase activity, acting on the CH-NH group of donors | nucleotide binding | flavin adenine dinucleotide binding | coenzyme binding | catalytic activity | anion binding | ion binding | organic cyclic compound binding | FAD binding | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
sulfur compound metabolic process | tetrahydrofolate metabolic process | methylenetetrahydrofolate reductase (NAD(P)H) activity | cellular process | oxidoreductase activity, acting on the CH-NH group of donors | sulfur amino acid biosynthetic process | cellular amino acid metabolic process | one-carbon metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | folic acid-containing compound metabolic process | cellular amino acid biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular biosynthetic process | pteridine-containing compound metabolic process | sulfur amino acid metabolic process | nitrogen compound metabolic process | small molecule metabolic process | methionine metabolic process | cellular amide metabolic process | biosynthetic process | carboxylic acid metabolic process | methionine biosynthetic process | metabolic process | oxidation-reduction process | organic substance metabolic process | tetrahydrofolate interconversion | organic acid metabolic process | cellular modified amino acid metabolic process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | cytosol | intracellular
