QuickView for MTOR;jsessionid=40384388D974A1E594C2559F5C1B1636;jsessionid=A7EDD230E31084A43E3AFE25C2184E7E (gene)
- Gene Symbol:
- MTOR
Canis lupus familiaris - Full name:
- mechanistic target of rapamycin (serine/threonine kinase)
- Synonyms:
- FRAP1
- Genomic Location:
- Chr 2: 87702638-87822598
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Saccharomyces cerevisiae , Bos taurus , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | nucleic acid binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ribonucleoprotein complex binding | ATP binding | anion binding | adenyl nucleotide binding | DNA binding | sequence-specific double-stranded DNA binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | ribosome binding | purine ribonucleoside triphosphate binding | phosphoprotein binding | protein binding | double-stranded DNA binding | transcription factor binding | transferase activity, transferring phosphorus-containing groups | rDNA binding | phosphotransferase activity, alcohol group as acceptor | RNA polymerase III type 1 promoter DNA binding | protein kinase activity | TFIIIC-class transcription factor binding | transferase activity | RNA polymerase III type 2 promoter DNA binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | RNA polymerase III regulatory region DNA binding | heterocyclic compound binding | RNA polymerase III type 3 promoter DNA binding | small molecule binding
GO Biological Process
response to extracellular stimulus | positive regulation of striated muscle cell differentiation | regulation of supramolecular fiber organization | multicellular organismal movement | adaptive immune response | cellular response to decreased oxygen levels | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | heart process | response to nutrient levels | TORC1 signaling | CD4-positive, alpha-beta T cell differentiation | positive regulation of cellular component organization | positive regulation of wound healing, spreading of epidermal cells | regulation of neurogenesis | CD4-positive, alpha-beta T cell activation | ruffle organization | developmental process involved in reproduction | muscle tissue development | intracellular signal transduction | regulation of cell development | regulation of localization | positive regulation of peptidyl-tyrosine phosphorylation | T cell lineage commitment | peptidyl-amino acid modification | regulation of transcription by RNA polymerase I | regulation of autophagy | regulation of immune system process | response to hormone | negative regulation of cellular process | positive regulation of developmental process | T-helper cell lineage commitment | cell differentiation | striated muscle cell development | nervous system development | cellular response to extracellular stimulus | multicellular organism growth | generation of precursor metabolites and energy | neurogenesis | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | generation of neurons | cardiac cell development | positive regulation of cellular biosynthetic process | cellular process | positive regulation of actin filament polymerization | lymphocyte differentiation | musculoskeletal movement | positive regulation of keratinocyte migration | regulation of cell motility | negative regulation of calcineurin-mediated signaling | regulation of calcium-mediated signaling | heart morphogenesis | negative regulation of macroautophagy | negative regulation of signaling | developmental growth | positive regulation of epithelial to mesenchymal transition | TOR signaling | T-helper 1 type immune response | immune system development | multicellular organismal reproductive process | response to leucine | response to hypoxia | cellular response to starvation | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of transcription by RNA polymerase III | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | gamete generation | positive regulation of muscle cell differentiation | muscle structure development | muscle cell differentiation | regulation of myotube differentiation | positive regulation of lamellipodium assembly | regulation of protein kinase B signaling | regulation of cellular process | positive regulation of lamellipodium organization | leukocyte activation | regulation of metabolic process | regulation of protein complex assembly | T cell differentiation involved in immune response | heart contraction | organic cyclic compound metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | cellular component organization | negative regulation of calcium-mediated signaling | positive regulation of epithelial cell migration | T cell activation | regulation of actin filament length | muscle contraction | response to stimulus | peptidyl-threonine phosphorylation | muscle cell development | alpha-beta T cell activation involved in immune response | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | cellular response to hypoxia | response to stress | leukocyte activation involved in immune response | germ cell development | cellular nitrogen compound biosynthetic process | posttranscriptional regulation of gene expression | positive regulation of lipid biosynthetic process | positive regulation of actin filament bundle assembly | response to peptide | cardiac muscle tissue development | response to starvation | protein serine/threonine kinase activity | positive regulation of transcription by RNA polymerase III | reproduction | cellular nitrogen compound metabolic process | regulation of macroautophagy | positive regulation of gliogenesis | blood circulation | negative regulation of metabolic process | regulation of cellular component size | positive regulation of RNA biosynthetic process | hemopoiesis | regulation of wound healing | protein modification process | cellular biosynthetic process | macromolecule modification | regulation of oligodendrocyte differentiation | voluntary musculoskeletal movement | positive regulation of stress fiber assembly | regulation of nucleic acid-templated transcription | T-helper cell differentiation | leukocyte differentiation | response to nitrogen compound | regulation of cell projection assembly | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | system development | cellular response to nutrient levels | response to oxygen levels | positive regulation of response to wounding | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of organelle organization | regulation of actin cytoskeleton organization | multicellular organism development | phosphorus metabolic process | response to amino acid | regulation of actin filament organization | regulation of catalytic activity | regulation of actomyosin structure organization | regulation of phosphorylation | T-helper 1 cell differentiation | cellular response to amino acid starvation | regulation of gene expression | cellular response to stress | alpha-beta T cell lineage commitment | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | cellular response to oxygen levels | regulation of myelination | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | small molecule metabolic process | positive regulation of cell projection organization | cardiocyte differentiation | positive regulation of protein complex assembly | negative regulation of calcineurin-NFAT signaling cascade | regulation of cellular component movement | alpha-beta T cell differentiation | response to nutrient | positive regulation of cell differentiation | nucleobase-containing small molecule metabolic process | positive regulation of cell migration | biosynthetic process | regulation of cellular protein metabolic process | cardiac muscle cell development | cellular response to leucine | phosphorylation | T cell activation involved in immune response | regulation of GTPase activity | cellular response to amino acid stimulus | pyrimidine nucleobase biosynthetic process | protein phosphorylation | post-embryonic development | phosphate-containing compound metabolic process | negative regulation of autophagy | striated muscle tissue development | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I | regulation of actin filament polymerization | cell activation involved in immune response | positive regulation of cytoskeleton organization | regulation of protein metabolic process | heart development | regulation of protein phosphorylation | regulation of locomotion | regulation of RNA metabolic process | striated muscle contraction | regulation of lipid biosynthetic process | striated muscle cell differentiation | lymphocyte activation | multicellular organism reproduction | T cell differentiation | heart valve development | protein metabolic process | positive regulation of protein modification process | regulation of growth | T cell selection | response to organic substance | regulation of hemopoiesis | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | response to insulin | anatomical structure development | positive regulation of neurogenesis | 'de novo' pyrimidine nucleobase biosynthetic process | cell projection organization | metabolic process | positive regulation of cell development | cell fate commitment | positive regulation of supramolecular fiber organization | regulation of RNA biosynthetic process | oxidation-reduction process | negative regulation of cell size | positive T cell selection | positive regulation of glial cell differentiation | immune response | nucleobase-containing compound metabolic process | protein kinase activity | positive regulation of cellular component biogenesis | heart valve morphogenesis | organic substance metabolic process | animal organ development | positive regulation of transcription by RNA polymerase I | alpha-beta T cell activation | regulation of calcineurin-NFAT signaling cascade | regulation of striated muscle cell differentiation | regulation of phosphate metabolic process | positive regulation of wound healing | T-helper 1 cell lineage commitment | cell activation | regulation of stress fiber assembly | regulation of epithelial cell migration | regulation of osteoclast differentiation | cardiac muscle cell differentiation | regulation of glial cell differentiation | regulation of response to wounding | regulation of cell communication | regulation of membrane permeability | regulation of gliogenesis | pyrimidine nucleobase metabolic process | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | cell development | energy reserve metabolic process | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cell size | anatomical structure morphogenesis | regulation of actin filament bundle assembly | positive regulation of plasma membrane bounded cell projection assembly | regulation of nervous system development | regulation of developmental process | energy derivation by oxidation of organic compounds | kinase activity | developmental process | regulation of muscle cell differentiation | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | positive regulation of oligodendrocyte differentiation | positive regulation of transcription, DNA-templated | positive regulation of protein polymerization | positive regulation of nucleic acid-templated transcription | regulation of lamellipodium assembly | response to organonitrogen compound | regulation of epithelial to mesenchymal transition | heterocycle metabolic process | response to amino acid starvation | regulation of lipid metabolic process | positive regulation of metabolic process | regulation of actin filament-based process | positive regulation of lipid metabolic process | cardiac muscle contraction | regulation of cell projection organization | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to leucine starvation | cellular response to organic substance | positive regulation of cell motility | regulation of translation | circulatory system development | sexual reproduction | regulation of cellular component organization | regulation of cytoskeleton organization | muscle system process | positive regulation of myotube differentiation | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | dendritic tree | protein-containing complex | cell projection | PML body | endomembrane system | nucleoplasm | vacuole | TORC2 complex | TORC1 complex | lytic vacuole | membrane-bounded organelle | nucleus | organelle | lysosome | membrane-enclosed lumen | cytosol | intracellular | membrane
