QuickView for MTOR;jsessionid=40384388D974A1E594C2559F5C1B1636;jsessionid=D3AEB1F349BA306E1EA20526CEF08EE0 (gene)
- Gene Symbol:
- TOR2
Saccharomyces cerevisiae - Full name:
- PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis
- Synonyms:
- DRR2, TOR2, YKL203C
- Genomic Location:
- Chr XI: 55936-63360
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Bos taurus , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
protein-containing complex binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | 1-phosphatidylinositol 4-kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
TORC1 signaling | actin filament-based process | positive regulation of Ras protein signal transduction | positive regulation of cellular component organization | intracellular signal transduction | regulation of localization | phosphatidylinositol metabolic process | actin cytoskeleton organization | regulation of autophagy | negative regulation of cellular process | phospholipid metabolic process | cellular process | negative regulation of macroautophagy | TOR signaling | regulation of cell cycle | ribosome biogenesis | negative regulation of cellular metabolic process | regulation of binding | regulation of cellular process | regulation of metabolic process | cellular component organization | cellular lipid metabolic process | positive regulation of protein binding | response to stimulus | actin filament reorganization | protein serine/threonine kinase activity | supramolecular fiber organization | regulation of macroautophagy | 1-phosphatidylinositol 4-kinase activity | negative regulation of metabolic process | protein modification process | macromolecule modification | positive regulation of GTP binding | establishment or maintenance of actin cytoskeleton polarity | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | actin filament organization | lipid metabolic process | regulation of small GTPase mediated signal transduction | cell cycle | organophosphate metabolic process | positive regulation of Rho protein signal transduction | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of snRNA pseudouridine synthesis | regulation of Rho protein signal transduction | phosphorylation | protein phosphorylation | establishment or maintenance of cell polarity | phosphate-containing compound metabolic process | negative regulation of autophagy | lipid phosphorylation | cell communication | regulation of cellular metabolic process | positive regulation of signal transduction | lipid modification | glycerolipid metabolic process | regulation of RNA metabolic process | positive regulation of transport | positive regulation of molecular function | actin filament reorganization involved in cell cycle | protein metabolic process | regulation of growth | regulation of intracellular signal transduction | positive regulation of small GTPase mediated signal transduction | metabolic process | actin cytoskeleton reorganization | regulation of vesicle-mediated transport | regulation of GTP binding | protein kinase activity | organic substance metabolic process | cytoskeleton organization | positive regulation of binding | positive regulation of Rho guanyl-nucleotide exchange factor activity | regulation of Rho guanyl-nucleotide exchange factor activity | regulation of cell communication | signaling | regulation of protein binding | regulation of endocytosis | cellular protein metabolic process | regulation of Ras protein signal transduction | phosphatidylinositol phosphorylation | glycerophospholipid metabolic process | kinase activity | organelle organization | regulation of cell growth | cellular protein modification process | regulation of transport | establishment or maintenance of cytoskeleton polarity | ribonucleoprotein complex biogenesis | cellular metabolic process | positive regulation of endocytosis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process
GO Cellular Component
cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | extrinsic component of membrane | organelle membrane | cell | cytoplasmic side of membrane | extrinsic component of plasma membrane | cytoplasm | intracellular organelle | protein-containing complex | fungal-type vacuole | plasma membrane | extrinsic component of cytoplasmic side of plasma membrane | vacuole | TORC2 complex | mitochondrion | TORC1 complex | lytic vacuole | membrane-bounded organelle | nucleus | organelle | cell periphery | fungal-type vacuole membrane | storage vacuole | intracellular | membrane | vacuolar membrane
