QuickView for Mecp2;jsessionid=F1C5C2C94B90D37ECB5899E05720B799;jsessionid=72EC865816B8F5C221B1E998E308EBBE (gene)
- Gene Symbol:
- Mecp2
Rattus norvegicus - Full name:
- methyl CpG binding protein 2
- Synonyms:
- methyl-CpG-binding protein 2, meCP-2 protein
- Genomic Location:
- Chr X: 159980589-160029651
- Description:
-
methyl-CpG-binding protein; binds to DNA that contains a single methyl-CpG pair
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-122a , Predicted Gene Targets for miR-129 , Predicted Gene Targets for miR-130 , Predicted Gene Targets for miR-132 , Predicted Gene Targets for miR-148 , Predicted Gene Targets for miR-181 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-192
- miRNA binding sites
(Source: miRecords):
GO Molecular Function
sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA secondary structure binding | enzyme binding | nucleic acid binding | mRNA binding | nucleotide binding | four-way junction DNA binding | unmethylated CpG binding | chromatin binding | protein domain specific binding | protein N-terminus binding | DNA binding | promoter-specific chromatin binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | siRNA binding | organic cyclic compound binding | protein binding | double-stranded DNA binding | DNA-binding transcription factor activity | transcription factor binding | chromatin DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded methylated DNA binding | methyl-CpG binding | histone deacetylase binding | heterocyclic compound binding | small molecule binding | RNA binding
GO Biological Process
RNA metabolic process | positive regulation of DNA methylation | brain development | regulation of supramolecular fiber organization | respiratory gaseous exchange | purine ribonucleotide metabolic process | response to radiation | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | microtubule cytoskeleton organization involved in mitosis | regulation of microtubule polymerization or depolymerization | long-term memory | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | behavioral fear response | regulation of cellular localization | regulation of synapse assembly | regulation of cell development | regulation of localization | subpallium development | positive regulation of histone H3-K9 methylation | response to isoquinoline alkaloid | positive regulation of dense core granule transport | regulation of programmed cell death | peptidyl-amino acid modification | phosphatidylglycerol metabolic process | hippocampus development | inositol metabolic process | smooth muscle cell differentiation | establishment of localization | regulation of DNA methylation | response to hormone | positive regulation of G2/M transition of mitotic cell cycle | negative regulation of neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | positive regulation of developmental process | negative regulation of astrocyte differentiation | response to potassium ion | social behavior | negative regulation of RNA biosynthetic process | response to metal ion | histone modification | microtubule cytoskeleton organization | cell differentiation | excitatory postsynaptic potential | respiratory tube development | negative regulation of dendrite development | defense response | nervous system development | response to drug | generation of precursor metabolites and energy | regulation of microtubule-based movement | neurogenesis | negative regulation of gene silencing by RNA | polyol metabolic process | regulation of organelle organization | positive regulation of cellular component movement | generation of neurons | phospholipid metabolic process | microtubule-based process | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | regulation of gene expression, epigenetic | negative regulation of gliogenesis | secretion | positive regulation of microtubule polymerization | regulation of production of miRNAs involved in gene silencing by miRNA | regulation of histone H3-K9 trimethylation | regulation of cell motility | localization | chromatin organization | positive regulation of synaptic transmission | regulation of respiratory gaseous exchange | cell maturation | nucleotide metabolic process | visual learning | chemical synaptic transmission | neuron development | negative regulation of developmental growth | synapse assembly | response to estradiol | ATP synthesis coupled electron transport | regulation of histone H3-K9 methylation | cellular respiration | ribose phosphate metabolic process | negative regulation of nucleic acid-templated transcription | learning | cellular response to potassium ion | macromolecule localization | regulation of histone modification | negative regulation of apoptotic process | response to hypoxia | nucleoside triphosphate metabolic process | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cell migration | ribonucleotide metabolic process | principal sensory nucleus of trigeminal nerve development | regulation of neuron projection development | diencephalon development | negative regulation of peptidyl-lysine acetylation | response to inorganic substance | positive regulation of anterograde dense core granule transport | negative regulation of cellular metabolic process | regulation of binding | regulation of cell differentiation | interspecies interaction between organisms | muscle structure development | muscle cell differentiation | negative regulation of histone methylation | negative regulation of cell motility | cellular amino acid metabolic process | cellular biogenic amine metabolic process | regulation of angiogenesis | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | gene silencing | regulation of metabolic process | gliogenesis | regulation of protein complex assembly | neurological system process involved in regulation of systemic arterial blood pressure | positive regulation of cell cycle phase transition | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | regulation of gene silencing by miRNA | regulation of G2/M transition of mitotic cell cycle | cellular component organization | negative regulation of dendrite extension | cellular lipid metabolic process | regulation of respiratory gaseous exchange by neurological system process | cellular response to metal ion | ventricular system development | positive regulation of branching morphogenesis of a nerve | head development | associative learning | regulation of histone methylation | regulation of vasculature development | response to stimulus | purine nucleotide metabolic process | respiratory system development | regulation of mitotic cell cycle phase transition | oligodendrocyte development | genetic imprinting | metencephalon development | positive regulation of protein metabolic process | mitotic spindle organization | response to cocaine | response to stress | cellular nitrogen compound biosynthetic process | alcohol metabolic process | regulation of cell proliferation | negative regulation of neuron projection development | electron transport chain | negative regulation of angiogenesis | regulation of cell cycle phase transition | positive regulation of synaptic plasticity | regulation of dendrite extension | cellular response to inorganic substance | secretion by cell | organic hydroxy compound transport | peptidyl-lysine acetylation | regulation of gene silencing | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | blood circulation | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular component assembly | pathogenesis | protein modification process | regulation of synapse structure or activity | amine metabolic process | modulation of chemical synaptic transmission | cellular biosynthetic process | regulation of morphogenesis of a branching structure | macromolecule modification | cell-cell signaling | regulation of intracellular transport | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | regulation of membrane potential | organic hydroxy compound metabolic process | response to nitrogen compound | negative regulation of neuron apoptotic process | lung alveolus development | regulation of cell cycle G2/M phase transition | response to light stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | positive regulation of organelle organization | negative regulation of growth | positive regulation of neuron projection development | multicellular organism development | protein acetylation | histone methylation | negative regulation of dendritic spine development | thalamus development | phosphorus metabolic process | neuromuscular process controlling posture | learning or memory | cerebellum development | lipid metabolic process | regulation of hormone levels | positive regulation of chromosome organization | proprioception | telencephalon development | positive regulation of cell cycle | positive regulation of mitotic cell cycle | regulation of neuron differentiation | regulation of gene expression | regulation of postsynaptic membrane potential | negative regulation of gene silencing by miRNA | methylation | regulation of microtubule nucleation | organic substance transport | response to lipid | nervous system process | cell cycle | regulation of blood pressure | synaptic signaling | organophosphate metabolic process | positive regulation of microtubule nucleation | regulation of systemic arterial blood pressure | negative regulation of gene expression, epigenetic | positive regulation of cellular metabolic process | regulation of smooth muscle cell differentiation | adult locomotory behavior | response to ammonium ion | negative regulation of primary miRNA processing | striatum development | regulation of synapse organization | regulation of nitrogen compound metabolic process | olfactory lobe development | regulation of cell migration | cardiolipin metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | positive regulation of cell projection organization | positive regulation of protein complex assembly | regulation of cellular component movement | regulation of transcription by RNA polymerase II | cellular response to alkaloid | positive regulation of cell cycle G2/M phase transition | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | synapse organization | negative regulation of binding | positive regulation of cell differentiation | regulation of endothelial cell migration | nucleobase-containing small molecule metabolic process | cognition | negative regulation of smooth muscle cell differentiation | trigeminal sensory nucleus development | histone acetylation | internal peptidyl-lysine acetylation | negative regulation of epithelial cell migration | biosynthetic process | locomotory behavior | sensory perception of pain | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | glial cell differentiation | hindbrain development | phosphorylation | carbohydrate metabolic process | startle response | regulation of dense core granule transport | positive regulation of dendritic spine development | response to xenobiotic stimulus | post-embryonic development | phosphate-containing compound metabolic process | negative regulation of blood vessel endothelial cell migration | cell communication | negative regulation of protein binding | regulation of cellular metabolic process | olfactory bulb development | regulation of neuron apoptotic process | regulation of respiratory system process | mitochondrial ATP synthesis coupled electron transport | positive regulation of cytoskeleton organization | regulation of protein metabolic process | heart development | limbic system development | positive regulation of cell proliferation | regulation of locomotion | glycerolipid metabolic process | regulation of RNA metabolic process | positive regulation of synapse assembly | positive regulation of transport | cerebral cortex development | positive regulation of retrograde dense core granule transport | negative regulation of cell growth | positive regulation of dendrite development | regulation of mitotic cell cycle | regulation of microtubule-based process | drug metabolic process | carboxylic acid metabolic process | neuron maturation | negative regulation of gene silencing | neuron differentiation | regulation of gene expression by genetic imprinting | multicellular organismal response to stress | fear response | protein metabolic process | DNA-binding transcription factor activity | positive regulation of protein modification process | regulation of growth | response to organic substance | negative regulation of cell projection organization | visual behavior | positive regulation of histone H3-K9 trimethylation | anatomical structure development | positive regulation of mitotic cell cycle phase transition | glutamine metabolic process | mitotic cell cycle | cell surface receptor signaling pathway | positive regulation of neurogenesis | cell projection organization | metabolic process | positive regulation of cell development | regulation of microtubule polymerization | positive regulation of supramolecular fiber organization | regulation of RNA biosynthetic process | developmental maturation | oxidation-reduction process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | cellular response to isoquinoline alkaloid | negative regulation of histone acetylation | oligodendrocyte differentiation | peptidyl-lysine modification | behavior | regulation of gene silencing by RNA | oxidative phosphorylation | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | positive regulation of histone modification | forebrain development | negative regulation of neuron differentiation | pallium development | negative regulation of cellular protein metabolic process | gene expression | negative regulation of cellular component movement | phosphatidylcholine metabolic process | cytoskeleton organization | regulation of chromosome organization | catecholamine secretion | response to alkaloid | regulation of organelle transport along microtubule | transcription, DNA-templated | positive regulation of intracellular transport | lung development | memory | adult behavior | negative regulation of protein metabolic process | regulation of dendrite development | sensory perception | regulation of epithelial cell migration | steroid metabolic process | regulation of glial cell differentiation | regulation of cell communication | regulation of blood vessel endothelial cell migration | regulation of gliogenesis | negative regulation of chromosome organization | negative regulation of molecular function | positive regulation of developmental growth | regulation of dendritic spine development | signaling | covalent chromatin modification | positive regulation of growth | glucocorticoid metabolic process | regulation of transcription, DNA-templated | regulation of protein binding | glial cell development | response to organic cyclic compound | neuromuscular process | cell development | regulation of developmental growth | internal protein amino acid acetylation | protein localization | organic acid metabolic process | regulation of production of small RNA involved in gene silencing by RNA | cellular protein metabolic process | hormone metabolic process | cellular macromolecule biosynthetic process | protein methylation | dendrite development | regulation of nervous system development | regulation of developmental process | glycerophospholipid metabolic process | positive regulation of DNA metabolic process | energy derivation by oxidation of organic compounds | developmental process | organelle organization | regulation of muscle cell differentiation | behavioral defense response | positive regulation of cell cycle process | regulation of cell growth | negative regulation of glial cell differentiation | cellular protein modification process | monoamine transport | mitochondrial electron transport, ubiquinol to cytochrome c | regulation of histone acetylation | negative regulation of transcription by RNA polymerase II | tube development | carbohydrate derivative metabolic process | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of protein polymerization | negative regulation of vasculature development | positive regulation of nucleic acid-templated transcription | negative regulation of endothelial cell migration | negative regulation of protein acetylation | response to organonitrogen compound | heterocycle metabolic process | positive regulation of dendrite extension | response to lead ion | central nervous system development | negative regulation of muscle cell differentiation | response to anesthetic | spinal cord development | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | positive regulation of metabolic process | chromosome organization | regulation of synaptic plasticity | positive regulation of neuron differentiation | chromatin silencing | regulation of cell projection organization | positive regulation of histone methylation | cellular metabolic process | long-term synaptic potentiation | ATP metabolic process | cellular response to organic substance | regulation of astrocyte differentiation | regulation of cell death | negative regulation of cell death | negative regulation of cell development | regulation of branching morphogenesis of a nerve | circulatory system development | spindle organization | negative regulation of locomotion | regulation of microtubule cytoskeleton organization | negative regulation of cell differentiation | regulation of cellular component organization | response to ionizing radiation | regulation of cytoskeleton organization | positive regulation of signaling | neural nucleus development | signal transduction | regulation of signaling | positive regulation of gene expression | negative regulation of production of miRNAs involved in gene silencing by miRNA | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | respiratory electron transport chain | regulation of chromatin organization
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | synapse | microtubule organizing center | cell | nuclear lumen | cytoplasm | intracellular organelle | centrosome | protein-containing complex | postsynapse | chromatin | nuclear chromosome | microtubule cytoskeleton | mitochondrion | gamma-tubulin complex | membrane-bounded organelle | heterochromatin | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | cytosol | cytoskeleton | intracellular
