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QuickView for Mre11;jsessionid=66AD74BD502FA3EEE82E5172B75FB0F1;jsessionid=38797FADDDDF1450AF9571B4A20FD9EA (gene)


Gene Symbol:
mre11 Schizosaccharomyces pombe Schizosaccharomyces pombe
Full name:
Rad32 nuclease
Synonyms:
rad32, SPAC13C5.07
Genomic Location:
Chr I: 436214-438369
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Gallus gallus Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_001018336
Protein Names
Q09683



GO Molecular Function

sequence-specific DNA binding | nuclease activity | sequence-specific single stranded DNA binding | single-stranded DNA endodeoxyribonuclease activity | cation binding | DNA secondary structure binding | nucleic acid binding | hydrolase activity | single-stranded DNA binding | Y-form DNA binding | single-stranded DNA 3'-5' exodeoxyribonuclease activity | catalytic activity | DNA end binding | double-stranded DNA exodeoxyribonuclease activity | exodeoxyribonuclease activity | deoxyribonuclease activity | DNA binding | single-stranded DNA exodeoxyribonuclease activity | hydrolase activity, acting on ester bonds | ion binding | organic cyclic compound binding | double-stranded DNA 3'-5' exodeoxyribonuclease activity | double-stranded telomeric DNA binding | endodeoxyribonuclease activity | protein binding | double-stranded DNA binding | manganese ion binding | 3'-5' exonuclease activity | endonuclease activity | transition metal ion binding | single-stranded telomeric DNA binding | exonuclease activity | metal ion binding | 3'-5'-exodeoxyribonuclease activity | heterocyclic compound binding | telomeric DNA binding

GO Biological Process

double-strand break repair | intra-S DNA damage checkpoint | regulation of cell cycle process | telomere maintenance | detection of stimulus | intracellular signal transduction | nuclease activity | negative regulation of cellular process | telomere capping | cellular process | single-stranded DNA endodeoxyribonuclease activity | mitotic DNA integrity checkpoint | regulation of cell cycle | anatomical structure homeostasis | regulation of cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | regulation of G2/M transition of mitotic cell cycle | cellular component organization | meiotic DNA double-strand break clipping | response to stimulus | regulation of mitotic cell cycle phase transition | chromosome segregation | response to stress | negative regulation of G2/M transition of mitotic cell cycle | mitotic G2 DNA damage checkpoint | regulation of cell cycle phase transition | reproduction | cellular nitrogen compound metabolic process | telomere organization | double-strand break repair via nonhomologous end joining | nucleic acid phosphodiester bond hydrolysis | single-stranded DNA 3'-5' exodeoxyribonuclease activity | DNA recombination | DNA repair | regulation of cell cycle G2/M phase transition | nitrogen compound metabolic process | reproductive process | negative regulation of mitotic cell cycle phase transition | double-strand break repair via homologous recombination | mitotic DNA damage checkpoint | negative regulation of cell cycle G2/M phase transition | meiotic DNA double-strand break processing involved in reciprocal meiotic recombination | sister chromatid segregation | cellular response to DNA damage stimulus | double-stranded DNA exodeoxyribonuclease activity | signal transduction in response to DNA damage | exodeoxyribonuclease activity | cellular response to stress | DNA double-strand break processing | cell cycle | deoxyribonuclease activity | mitochondrial double-strand break repair via homologous recombination | single-stranded DNA exodeoxyribonuclease activity | signal transduction involved in cell cycle checkpoint | double-stranded DNA 3'-5' exodeoxyribonuclease activity | nuclear chromosome segregation | DNA strand elongation | cell communication | endodeoxyribonuclease activity | base-excision repair | homeostatic process | meiotic DNA double-strand break formation | regulation of mitotic cell cycle | mitotic G2/M transition checkpoint | telomeric 3' overhang formation | DNA metabolic process | reciprocal meiotic recombination | mitotic cell cycle | DNA damage response, detection of DNA damage | nuclear division | metabolic process | 3'-5' exonuclease activity | negative regulation of mitotic cell cycle | nucleobase-containing compound metabolic process | organic substance metabolic process | endonuclease activity | meiosis I | negative regulation of cell cycle | meiotic cell cycle | signaling | homologous recombination | signal transduction involved in DNA damage checkpoint | recombinational repair | organelle organization | sister chromatid cohesion | exonuclease activity | heterocycle metabolic process | 3'-5'-exodeoxyribonuclease activity | chromosome organization | double-strand break repair involved in meiotic recombination | meiotic DNA double-strand break processing | mitotic cell cycle checkpoint | cellular metabolic process | negative regulation of cell cycle process | DNA damage checkpoint | cell cycle checkpoint | signal transduction | macromolecule metabolic process

GO Cellular Component

site of DNA damage | chromosome | intracellular membrane-bounded organelle | subtelomeric heterochromatin | cell | nuclear lumen | intracellular organelle | protein-containing complex | chromatin | nuclear chromosome | chromosome, telomeric region | site of double-strand break | membrane-bounded organelle | heterochromatin | nucleus | organelle | membrane-enclosed lumen | nuclear chromosome, telomeric region | intracellular | Mre11 complex