QuickView for N-Myc;jsessionid=EB627945F66CD75D64FCE338644C2702;jsessionid=86504240969D82087E60CF9D0D528AC8 (gene)
- Gene Symbol:
- Mycn
Rattus norvegicus - Full name:
- MYCN proto-oncogene, bHLH transcription factor
- Synonyms:
- N-myc, Nmuc1, Nmyc, N-myc proto-oncogene protein, Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc), v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, v-myc myelocytomatosis viral related oncogene, neuroblastoma derived
- Genomic Location:
- Chr 6: 36508262-36514071
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
ZIC2_01 , ZIC3_01 , AP2_Q3 , AP4_Q6_01 , AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D , GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D , TGGTGCT_MIR29A_MIR29B_MIR29C , CAGTATT_MIR200B_MIR200C_MIR429 , TTTGCAC_MIR19A_MIR19B , CACTTTG_MIR520G_MIR520H
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for let-7 , Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-134 , Predicted Gene Targets for miR-142-5p , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-145 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-193 , Predicted Gene Targets for miR-20
GO Molecular Function
sequence-specific DNA binding | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | limb development | positive regulation of macromolecule biosynthetic process | regulation of neurogenesis | regulation of inner ear receptor cell differentiation | regulation of cell development | morphogenesis of an epithelium | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of astrocyte differentiation | embryonic appendage morphogenesis | cell differentiation | respiratory tube development | nervous system development | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | negative regulation of gliogenesis | epithelial tube morphogenesis | limb morphogenesis | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cartilage condensation | embryonic limb morphogenesis | respiratory system development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | regulation of epithelial cell differentiation | embryonic skeletal system development | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cartilage development | cellular biosynthetic process | embryo development | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | multicellular organism development | regulation of neuron differentiation | regulation of gene expression | regulation of epidermis development | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | chordate embryonic development | regulation of cellular metabolic process | skeletal system morphogenesis | positive regulation of cell proliferation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | embryonic morphogenesis | embryonic organ morphogenesis | regulation of inner ear auditory receptor cell differentiation | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | tissue morphogenesis | branching morphogenesis of an epithelial tube | anatomical structure development | embryonic skeletal system morphogenesis | metabolic process | regulation of RNA biosynthetic process | embryonic organ development | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | connective tissue development | negative regulation of gene expression | animal organ development | gene expression | transcription, DNA-templated | lung development | morphogenesis of a branching epithelium | regulation of glial cell differentiation | regulation of gliogenesis | regulation of transcription, DNA-templated | embryonic digit morphogenesis | morphogenesis of a branching structure | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | regulation of mesenchymal cell proliferation | developmental process | cell aggregation | negative regulation of glial cell differentiation | tube development | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | positive regulation of mesenchymal cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | skeletal system development | cellular metabolic process | regulation of astrocyte differentiation | regulation of cell death | negative regulation of cell development | negative regulation of cell differentiation | regulation of epidermal cell differentiation | negative regulation of reactive oxygen species metabolic process | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | intracellular organelle | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
