QuickView for NM_001143760;jsessionid=54FB64CB256BD5C17E5470C7222C5E56;jsessionid=BE6168EB28CE30E61224628E3D828449 (gene)

Gene Symbol:

Eif5a Mus musculus

Full name:

eukaryotic translation initiation factor 5A

Synonyms:

AA410058, D19Wsu54e, Eif4d, Eif5a1, eIF-4D, eIF-5A, eIF-5A-1, eIF-5A1, eukaryotic translation initiation factor 5A-1

Genomic Location:

Chr 11: 69730224-69734843

Description:

This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a modified lysine residue called hypusine, which appears to be necessary for its function. Alternatively spliced transcript variants ha...

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This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a modified lysine residue called hypusine, which appears to be necessary for its function. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2, 5, and 19.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SP1_01 ,  ELK1_02 ,  CETS1P54_01 ,  NFKAPPAB65_01 ,  CREL_01 ,  NFKAPPAB_01 ,  MZF1_01 ,  NRF2_01 ,  CREB_02 ,  LYF1_01 ,  RORA2_01 ,  NFKB_C ,  USF_C ,  SREBP1_02 ,  EGR1_01 ,  NGFIC_01 ,  MYCMAX_B ,  PAX3_B ,  ETS2_B ,  GABP_B ,  PAX4_01 ,  E2F1_Q4 ,  VDR_Q3 ,  ZIC1_01 ,  AP2REP_01 ,  MAZR_01 ,  STAT3_02 ,  E2F_03 ,  HOXA4_Q2 ,  MTF1_Q4 ,  NRF1_Q6 ,  E4F1_Q6 ,  ICSBP_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  COREBINDINGFACTOR_Q6 ,  AML_Q6 ,  NFKB_Q6_01 ,  USF_Q6_01 ,  CREB_Q3 ,  E2F_Q4_01 ,  E2F_Q6_01 ,  E2F1_Q3_01 ,  DR3_Q4 ,  GGGACCA_MIR133A_MIR133B ,  TCCCRNNRTGC_UNKNOWN ,  TGCGCANK_UNKNOWN ,  YGCANTGCR_UNKNOWN ,  RACCACAR_AML_Q6 ,  TAATTA_CHX10_01 ,  CAGGTG_E12_Q6 ,  GTGACGY_E4F1_Q6 ,  SCGGAAGY_ELK1_02 ,  RYTTCCTG_ETS2_B ,  MGGAAGTG_GABP_B ,  STTTCRNTTT_IRF_Q6 ,  GGGAGGRR_MAZ_Q6 ,  TGACAGNY_MEIS1_01 ,  RCGCANGCGY_NRF1_Q6 ,  GGGTGGRR_PAX4_03 ,  CTAWWWATA_RSRFC4_Q2 ,  TAAWWATAG_RSRFC4_Q2 ,  GGGCGGR_SP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-133 ,  Predicted Gene Targets for miR-495

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