QuickView for NOD2;jsessionid=D2B2803848631C6706696A45CB435EAD;jsessionid=AEA021859AD1262AD2736915D121B068;jsessionid=A1EA8A346A215779A310518DD59BFB19 (gene)
- Gene Symbol:
- NOD2
Bos taurus - Full name:
- nucleotide-binding oligomerization domain containing 2
- Synonyms:
- CARD15
- Genomic Location:
- Chr 18: 18141356-18171153
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
actin binding | kinase binding | peptide binding | protein kinase binding | muramyl dipeptide binding | enzyme binding | ribonucleotide binding | nucleotide binding | CARD domain binding | carbohydrate derivative binding | protein domain specific binding | ATP binding | Hsp70 protein binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | amide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | peptidoglycan binding | glycosaminoglycan binding | Hsp90 protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heat shock protein binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of immune response | nucleotide-binding oligomerization domain containing signaling pathway | regulation of interleukin-1 beta production | positive regulation of macromolecule biosynthetic process | detection of stimulus | cellular response to muramyl dipeptide | regulation of B cell activation | immune response-regulating signaling pathway | intracellular signal transduction | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | defense response to other organism | establishment of localization | regulation of immune system process | epithelial structure maintenance | positive regulation of lymphocyte activation | defense response | response to drug | positive regulation of interleukin-1 beta secretion | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of protein secretion | tissue homeostasis | innate immune response-activating signal transduction | positive regulation of cellular biosynthetic process | cellular process | secretion | localization | protein transport | macromolecule localization | positive regulation of nitrogen compound metabolic process | anatomical structure homeostasis | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | regulation of type 2 immune response | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | positive regulation of tumor necrosis factor production | positive regulation of interleukin-17 production | regulation of peptide secretion | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | positive regulation of interleukin-1 beta production | positive regulation of NIK/NF-kappaB signaling | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | detection of peptidoglycan | positive regulation of protein polyubiquitination | multicellular organismal homeostasis | regulation of protein ubiquitination | response to peptide | positive regulation of cell-cell adhesion | response to muramyl dipeptide | positive regulation of cell activation | activation of innate immune response | secretion by cell | positive regulation of cytokine secretion | response to molecule of bacterial origin | positive regulation of T cell activation | immune response-activating signal transduction | regulation of protein transport | positive regulation of RNA biosynthetic process | regulation of peptide transport | regulation of cell adhesion | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | regulation of cellular response to stress | response to nitrogen compound | response to external biotic stimulus | detection of molecule of bacterial origin | regulation of signal transduction | detection of chemical stimulus | pattern recognition receptor signaling pathway | regulation of MAPK cascade | positive regulation of inflammatory response | maintenance of gastrointestinal epithelium | regulation of phosphorylation | regulation of T cell activation | regulation of gene expression | positive regulation of secretion | organic substance transport | cellular response to peptide | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | digestive system process | regulation of lymphocyte activation | response to peptidoglycan | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | peptide transport | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | positive regulation of cytokine production involved in inflammatory response | detection of muramyl dipeptide | regulation of cytokine production involved in inflammatory response | regulation of cellular protein metabolic process | positive regulation of interleukin-1 secretion | cytokine production involved in immune response | regulation of tumor necrosis factor production | cellular response to drug | response to bacterium | regulation of interleukin-1 production | peptide secretion | cell communication | regulation of cellular metabolic process | positive regulation of interleukin-1 production | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | homeostatic process | positive regulation of establishment of protein localization | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of B cell activation | positive regulation of transport | cytokine secretion involved in immune response | nucleotide-binding oligomerization domain containing 2 signaling pathway | positive regulation of molecular function | regulation of cytokine secretion | cytokine production | activation of immune response | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | regulation of establishment of protein localization | positive regulation of type 2 immune response | positive regulation of protein modification process | response to organic substance | regulation of innate immune response | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | cytokine secretion | regulation of interleukin-1 beta secretion | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | amide transport | regulation of secretion | positive regulation of interleukin-6 production | regulation of protein K63-linked ubiquitination | immune response | regulation of cell activation | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | detection of bacterium | regulation of phosphate metabolic process | positive regulation of protein K63-linked ubiquitination | establishment of protein localization | positive regulation of cytokine production | regulation of JNK cascade | positive regulation of MAPK cascade | intracellular receptor signaling pathway | positive regulation of protein transport | regulation of stress-activated MAPK cascade | regulation of cell communication | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | protein localization | positive regulation of phosphorylation | regulation of cytokine production | response to biotic stimulus | detection of biotic stimulus | digestion | regulation of transport | positive regulation of transcription, DNA-templated | regulation of cell-cell adhesion | innate immune response | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | immune system process | cellular response to organic substance | regulation of protein localization | regulation of cell death | protein secretion | regulation of interleukin-6 production | regulation of inflammatory response | positive regulation of leukocyte cell-cell adhesion | positive regulation of protein ubiquitination | regulation of I-kappaB kinase/NF-kappaB signaling | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | positive regulation of gamma-delta T cell activation | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | COP9 signalosome | cell | cytoplasm | intracellular organelle | Golgi apparatus | protein-containing complex | endomembrane system | plasma membrane | vesicle | membrane-bounded organelle | nucleus | organelle | cell periphery | basolateral plasma membrane | cytosol | cell surface | cytoskeleton | intracellular | membrane
