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QuickView for NR3C2;jsessionid=541FFECE5C9E3AAC8E46EE8CB25C010D;jsessionid=1985364C8956030CED7361E89F9ADD96 (gene)


Gene Symbol:
Nr3c2 Rattus norvegicus Rattus norvegicus
Full name:
nuclear receptor subfamily 3, group C, member 2
Synonyms:
MCR, Mlr, mineralocorticoid receptor, MR, Mineralocorticoid receptor (aldosterone receptor)
Genomic Location:
Chr 19: 32527752-32875369
Description:
mineralocorticoid receptor; involved in renal sodium and water regulation
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
CMYB_01 AACTTT_UNKNOWN IRF1_01 IRF2_01 IK1_01 CDPCR1_01 CDPCR3HD_01 ACCTGTTG_UNKNOWN GATA1_03 OCT1_04
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-101 Predicted Gene Targets for miR-129 Predicted Gene Targets for miR-130 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-144 Predicted Gene Targets for miR-153 Predicted Gene Targets for miR-186 Predicted Gene Targets for miR-19 Predicted Gene Targets for miR-205 Predicted Gene Targets for miR-30


Transcripts Names
NM_013131
Protein Names
Q64174
P22199
Q63763



GO Molecular Function

sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nuclear receptor activity | cation binding | transcription factor activity, direct ligand regulated sequence-specific DNA binding | nucleic acid binding | lipid binding | steroid hormone receptor activity | DNA binding | signaling receptor activity | mineralocorticoid receptor activity | identical protein binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | hormone binding | protein binding | protein homodimerization activity | zinc ion binding | double-stranded DNA binding | DNA-binding transcription factor activity | protein dimerization activity | transition metal ion binding | steroid binding | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | response to hormone | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cellular chemical homeostasis | hormone-mediated signaling pathway | cellular process | nuclear receptor activity | cellular homeostasis | cellular sodium ion homeostasis | transcription factor activity, direct ligand regulated sequence-specific DNA binding | regulation of cellular process | cellular response to lipid | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | steroid hormone receptor activity | steroid hormone mediated signaling pathway | cellular biosynthetic process | metal ion homeostasis | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | sodium ion homeostasis | nitrogen compound metabolic process | regulation of gene expression | response to lipid | excretion | cellular ion homeostasis | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | mineralocorticoid receptor activity | biosynthetic process | aromatic compound biosynthetic process | mineralocorticoid receptor signaling pathway | cation homeostasis | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | homeostatic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | response to organic substance | metabolic process | regulation of RNA biosynthetic process | chemical homeostasis | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | ion homeostasis | cellular response to steroid hormone stimulus | transcription, DNA-templated | intracellular receptor signaling pathway | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular monovalent inorganic cation homeostasis | cellular macromolecule biosynthetic process | intracellular steroid hormone receptor signaling pathway | cellular metal ion homeostasis | heterocycle metabolic process | cellular metabolic process | cellular response to organic substance | response to steroid hormone | signal transduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | membrane