QuickView for NT-4;jsessionid=F02E9F16E49BB2C492C958E7AB540FCC;jsessionid=99FC3D43F60323EA66FB1C6CEA222257;jsessionid=BAE1299D0BE14977DD69C6ED0FABFC15 (gene)

Gene Symbol:

Ntf5 Mus musculus

Full name:

neurotrophin 5

Synonyms:

2900040K06Rik, AI462899, NT-4, NT-5, NT4, NT4/5, Ntf-5, Ntf4, neurotrophin-4, neutrophic factor 4

Genomic Location:

Chr 7: 52669065-52672549

Description:

This gene encodes a secreted protein belonging to the neurotrophin family of structurally related molecules that play a crucial role in the control of neuronal numbers and of dendritic growth. The encoded preproprotein undergoes post-translational processing to generate non-covalently associated homodimeric functional protein. Mice deficient in the...

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This gene encodes a secreted protein belonging to the neurotrophin family of structurally related molecules that play a crucial role in the control of neuronal numbers and of dendritic growth. The encoded preproprotein undergoes post-translational processing to generate non-covalently associated homodimeric functional protein. Mice deficient in the encoded protein exhibit a loss of sensory neurons in the nodose-petrosal and geniculate ganglia, have deficits in long-term memory and hippocampal long-lasting long-term potentiation.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA3_01 ,  GATA1_02 ,  SP1_Q6 ,  STAT_01 ,  LMO2COM_02 ,  STAT5A_01 ,  STAT5B_01 ,  STAT5A_02 ,  CACBINDINGPROTEIN_Q6 ,  SMAD4_Q6 ,  AP2_Q6_01 ,  SP1_Q6_01 ,  SP1_Q4_01 ,  SP1_Q2_01 ,  T3R_Q6 ,  TGACATY_UNKNOWN ,  TTCYRGAA_UNKNOWN ,  CAGCTG_AP4_Q5 ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  RYTTCCTG_ETS2_B ,  GATAAGR_GATA_C ,  RGAANNTTC_HSF1_01 ,  GGGTGGRR_PAX4_03 ,  TTCYNRGAA_STAT5B_01 ,  WGGAATGY_TEF1_Q6

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