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QuickView for NTRK1;jsessionid=7E9A961A4955B9D900AC1C4AD50DEC06;jsessionid=968A8ED8535C029EA4B9499CA8D113F3;jsessionid=87E727971D8BE4D20C48E09A842C8AE6 (gene)


Gene Symbol:
Ntrk1 Mus musculus Mus musculus
Full name:
neurotrophic tyrosine kinase, receptor, type 1
Synonyms:
C80751, Tkr, TrkA, trk, high affinity nerve growth factor receptor
Genomic Location:
Chr 3: 87582166-87599084
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

nerve growth factor binding | kinase binding | neurotrophin binding | transmembrane receptor protein tyrosine kinase activity | transmembrane signaling receptor activity | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | cytokine receptor binding | growth factor binding | catalytic activity | ATP binding | neurotrophin receptor binding | anion binding | adenyl nucleotide binding | ephrin receptor activity | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | GPI-linked ephrin receptor activity | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | protein homodimerization activity | nerve growth factor receptor activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | neurotrophin receptor activity | neurotrophin p75 receptor binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

response to extracellular stimulus | behavioral response to pain | regulation of ERK1 and ERK2 cascade | cell morphogenesis | chemosensory behavior | response to nutrient levels | positive regulation of Ras protein signal transduction | detection of stimulus | positive regulation of cellular component organization | regulation of neurogenesis | neuron projection morphogenesis | developmental process involved in reproduction | regulation of synapse assembly | regulation of cell development | positive regulation of DNA-binding transcription factor activity | gonad development | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | detection of mechanical stimulus involved in sensory perception | nervous system development | response to drug | cell part morphogenesis | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | generation of neurons | B cell differentiation | sensory perception of mechanical stimulus | regulation of neuron death | behavioral response to formalin induced pain | positive regulation of GTPase activity | cellular process | lymphocyte differentiation | cell projection morphogenesis | positive regulation of synaptic transmission | negative regulation of signaling | neuron development | reproductive system development | immune system development | negative regulation of apoptotic process | axon guidance | Sertoli cell differentiation | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | tissue development | regulation of cell differentiation | axonogenesis involved in innervation | autonomic nervous system development | regulation of angiogenesis | peptidyl-tyrosine autophosphorylation | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | response to nerve growth factor | positive regulation of cellular protein metabolic process | epithelium development | ephrin receptor signaling pathway | cellular component organization | development of primary sexual characteristics | regulation of vasculature development | response to stimulus | cell morphogenesis involved in neuron differentiation | nerve growth factor signaling pathway | response to pain | positive regulation of protein metabolic process | response to stress | neuron projection guidance | regulation of cell proliferation | sensory perception of temperature stimulus | epithelial cell development | circadian rhythm | programmed cell death | reproduction | response to temperature stimulus | rhythmic process | cellular response to toxic substance | hemopoiesis | protein modification process | regulation of synapse structure or activity | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | macromolecule modification | detection of temperature stimulus involved in sensory perception | regulation of nucleic acid-templated transcription | leukocyte differentiation | detection of abiotic stimulus | locomotion | negative regulation of neuron apoptotic process | response to nicotine | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | positive regulation of neuron projection development | multicellular organism development | response to activity | regulation of synaptic transmission, glutamatergic | regulation of MAPK cascade | phosphorus metabolic process | learning or memory | regulation of catalytic activity | cellular response to nerve growth factor stimulus | regulation of phosphorylation | mechanoreceptor differentiation | detection of mechanical stimulus involved in sensory perception of pain | regulation of small GTPase mediated signal transduction | regulation of neuron differentiation | regulation of gene expression | axon development | nervous system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of synapse organization | ephrin receptor activity | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | axonogenesis | positive regulation of hydrolase activity | positive regulation of cell differentiation | cognition | B cell activation | innervation | sensory perception of pain | regulation of cellular protein metabolic process | neurotrophin signaling pathway | phosphorylation | response to toxic substance | detection of temperature stimulus involved in sensory perception of pain | regulation of GTPase activity | programmed cell death involved in cell development | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | cellular response to drug | cell communication | regulation of cellular metabolic process | sympathetic nervous system development | regulation of neuron apoptotic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | GPI-linked ephrin receptor activity | regulation of RNA metabolic process | positive regulation of synapse assembly | cellular response to nicotine | lymphocyte activation | protein tyrosine kinase activity | positive regulation of molecular function | neuron differentiation | nerve growth factor receptor activity | development of primary male sexual characteristics | multicellular organismal response to stress | protein metabolic process | positive regulation of protein modification process | response to organic substance | neurotrophin TRK receptor signaling pathway | male sex differentiation | response to mechanical stimulus | detection of stimulus involved in sensory perception | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | Sertoli cell development | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | positive regulation of small GTPase mediated signal transduction | cell projection organization | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | negative regulation of programmed cell death | male gonad development | behavior | positive regulation of cell death | protein kinase activity | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | cell death | animal organ development | nerve development | positive regulation of NF-kappaB transcription factor activity | positive regulation of ERK1 and ERK2 cascade | positive regulation of programmed cell death | regulation of phosphate metabolic process | detection of mechanical stimulus | neurotrophin receptor activity | cell activation | positive regulation of MAPK cascade | sensory perception | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | cell development | positive regulation of phosphorylation | cellular protein metabolic process | regulation of Ras protein signal transduction | anatomical structure morphogenesis | reproductive structure development | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | cellular protein modification process | detection of temperature stimulus | negative regulation of cell proliferation | epithelial cell differentiation | response to electrical stimulus | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | sex differentiation | negative regulation of cell death | chemotaxis | positive regulation of angiogenesis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | dendrite | late endosome | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | dendritic tree | protein-containing complex | cell projection | endomembrane system | plasma membrane | vesicle | integral component of plasma membrane | endosome | membrane-bounded organelle | organelle | cell periphery | axon | early endosome | intracellular vesicle | cell surface | intracellular | membrane | intrinsic component of plasma membrane