QuickView for NUDT1;jsessionid=0F4ED5A3404A8DBC6D273D4A274739C6;jsessionid=B09288D11D6DCEF835C9B6A5DCAA8927;jsessionid=E2499F036FA7044788D711EA19ED8AD2;jsessionid=6686DD73C7C84D320D82C592A6F9933D (gene)
- Gene Symbol:
- Nudt1
Rattus norvegicus - Full name:
- nudix hydrolase 1
- Synonyms:
- Mth1, 7,8-dihydro-8-oxoguanine triphosphatase, 2-hydroxy-dATP diphosphatase, 8-oxo-dGTPase, mutT human homolog (8-oxo-dGTPase), nucleoside diphosphate-linked moiety X motif 1, nudix (nucleoside diphosphate linked moiety X)-type motif 1, nudix motif 1, nudix-type motif 1
- Genomic Location:
- Chr 12: 14775536-14778845
- Description:
-
degrades 8-oxoguanine-containing deoxyribonucleoside triphosphate, a potentially mutagenic substrate for DNA synthesis; may control spontaneous mutagenesis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
GO Molecular Function
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity | cation binding | 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity | 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity | snoRNA binding | nucleic acid binding | 2-hydroxy-adenosine triphosphate pyrophosphatase activity | hydrolase activity | pyrophosphatase activity | catalytic activity | nucleoside-triphosphatase activity | ion binding | organic cyclic compound binding | GTPase activity | ATP diphosphatase activity | nucleoside-triphosphate diphosphatase activity | hydrolase activity, acting on acid anhydrides | GTP diphosphatase activity | m7G(5')pppN diphosphatase activity | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | RNA binding
GO Biological Process
response to extracellular stimulus | nucleoside phosphate catabolic process | developmental process involved in reproduction | gonad development | response to metal ion | deoxyribonucleoside triphosphate metabolic process | cellular response to extracellular stimulus | organophosphate catabolic process | cellular process | organic substance catabolic process | nucleotide metabolic process | reproductive system development | carbohydrate derivative catabolic process | dGTP catabolic process | nucleoside triphosphate metabolic process | response to inorganic substance | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | development of primary sexual characteristics | response to stimulus | purine nucleotide metabolic process | response to stress | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | deoxyribose phosphate catabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | DNA repair | system development | nitrogen compound metabolic process | purine deoxyribonucleoside triphosphate catabolic process | reproductive process | multicellular organism development | phosphorus metabolic process | cellular response to DNA damage stimulus | cellular response to stress | organophosphate metabolic process | deoxyribonucleotide metabolic process | small molecule metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | response to cadmium ion | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | cell communication | aromatic compound catabolic process | deoxyribonucleoside triphosphate catabolic process | development of primary male sexual characteristics | male sex differentiation | DNA metabolic process | anatomical structure development | metabolic process | male gonad development | dGTP metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | DNA protection | dATP catabolic process | organonitrogen compound catabolic process | dATP metabolic process | nucleoside triphosphate catabolic process | reproductive structure development | developmental process | carbohydrate derivative metabolic process | deoxyribonucleotide catabolic process | heterocycle metabolic process | cellular metabolic process | sex differentiation | aging | purine nucleotide catabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
secretory granule | mitochondrial matrix | intracellular membrane-bounded organelle | organelle membrane | nuclear membrane | cytoplasmic vesicle | cell | cytoplasm | acrosomal vesicle | intracellular organelle | secretory vesicle | endomembrane system | plasma membrane | nuclear envelope | vesicle | mitochondrion | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell periphery | membrane-enclosed lumen | cytosol | intracellular vesicle | intracellular | membrane
