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QuickView for Nf1;jsessionid=7575AA897BCCB83D5D481E5F0047E2F4;jsessionid=E1557027D50CAFA0CF86D6D3D4A5B697 (gene)


Gene Symbol:
NF1 Gallus gallus Gallus gallus
Full name:
neurofibromin 1
Synonyms:
N/A
Genomic Location:
Chr 19: 8971608-9051414
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
XM_415914
Protein Names
No proteins found.



GO Molecular Function

enzyme activator activity | cation binding | GTPase activator activity | lipid binding | GTPase regulator activity | phospholipid binding | molecular function regulator | phosphatidylethanolamine binding | anion binding | phosphatidylcholine binding | ion binding | enzyme regulator activity

GO Biological Process

positive regulation of cyclase activity | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | negative regulation of phosphorylation | brain development | response to radiation | regulation of extrinsic apoptotic signaling pathway in absence of ligand | negative regulation of intracellular transport | regulation of intracellular protein transport | negative regulation of MAPK cascade | negative regulation of immune system process | actin filament-based process | extracellular structure organization | observational learning | regulation of neurogenesis | neurotransmitter secretion | regulation of cellular localization | positive regulation of lyase activity | muscle tissue development | intracellular signal transduction | enzyme activator activity | positive regulation of apoptotic process | regulation of cell development | regulation of localization | regulation of programmed cell death | eye development | Schwann cell differentiation | forebrain morphogenesis | actin cytoskeleton organization | establishment of localization | regulation of immune system process | negative regulation of neuroblast proliferation | astrocyte development | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | negative regulation of astrocyte differentiation | regulation of protein import | cell differentiation | positive regulation of epithelial cell proliferation | negative regulation of cell-matrix adhesion | nervous system development | negative regulation of protein phosphorylation | neurogenesis | negative regulation of osteoclast differentiation | positive regulation of endothelial cell proliferation | generation of neurons | regulation of neuroblast proliferation | blood vessel morphogenesis | regulation of bone remodeling | regulation of neuron death | positive regulation of GTPase activity | cellular process | negative regulation of gliogenesis | secretion | peripheral nervous system development | monocarboxylic acid transport | regulation of cell motility | localization | axon ensheathment | extrinsic apoptotic signaling pathway | negative regulation of protein import into nucleus | negative regulation of signaling | visual learning | chemical synaptic transmission | regulation of neuronal synaptic plasticity | dicarboxylic acid transport | anion transport | GTPase activator activity | learning | negative regulation of secretion | response to hypoxia | positive regulation of catalytic activity | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | regulation of myeloid cell differentiation | negative regulation of cell migration | establishment of localization in cell | negative regulation of establishment of protein localization | negative regulation of cellular metabolic process | tissue development | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | negative regulation of neurotransmitter transport | muscle structure development | autonomic nervous system development | skeletal muscle organ development | negative regulation of cell motility | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | hepaticobiliary system development | small GTPase mediated signal transduction | epithelium development | glutamate secretion, neurotransmission | cellular component organization | MAPK cascade | negative regulation of protein localization to nucleus | urogenital system development | head development | gamma-aminobutyric acid secretion, neurotransmission | associative learning | regulation of vasculature development | response to stimulus | negative regulation of protein transport | vasculature development | acid secretion | regulation of cellular protein localization | regulation of long-term synaptic potentiation | signal transduction by protein phosphorylation | negative regulation of cell adhesion | GTPase regulator activity | negative regulation of intracellular protein transport | response to stress | negative regulation of protein kinase activity | skeletal muscle tissue development | regulation of cell proliferation | negative regulation of angiogenesis | tube morphogenesis | regulation of Rac protein signal transduction | ensheathment of neurons | programmed cell death | phosphatidylinositol-mediated signaling | supramolecular fiber organization | cellular localization | secretion by cell | cardiovascular system development | response to temperature stimulus | extracellular matrix organization | negative regulation of transport | extrinsic apoptotic signaling pathway via death domain receptors | regulation of protein transport | brain morphogenesis | negative regulation of metabolic process | negative regulation of hemopoiesis | protein modification process | regulation of peptide transport | modulation of chemical synaptic transmission | regulation of cell adhesion | kidney development | embryo development | macromolecule modification | cell-cell signaling | regulation of oligodendrocyte differentiation | regulation of intracellular transport | molecular function regulator | blood vessel development | regulation of neurotransmitter levels | regulation of long-term neuronal synaptic plasticity | apoptotic process | response to light stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of secretion by cell | negative regulation of phosphate metabolic process | myelination | multicellular organism development | negative regulation of catalytic activity | regulation of synaptic transmission, GABAergic | regulation of MAPK cascade | phosphorus metabolic process | learning or memory | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | gamma-aminobutyric acid secretion | regulation of phosphorylation | negative regulation of cellular protein localization | wound healing | telencephalon development | artery development | regulation of small GTPase mediated signal transduction | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | organic substance transport | cellular response to stress | nervous system process | synaptic signaling | regulation of stem cell proliferation | cellular response to heat | animal organ morphogenesis | liver development | negative regulation of myeloid cell differentiation | regulation of protein localization to nucleus | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | negative regulation of protein serine/threonine kinase activity | regulation of cellular component movement | forebrain astrocyte development | pigmentation | organic acid transport | positive regulation of hydrolase activity | regulation of endothelial cell migration | synaptic transmission, glutamatergic | amygdala development | cognition | positive regulation of adenylate cyclase activity | negative regulation of neurotransmitter secretion | neural tube development | regulation of cellular protein metabolic process | negative regulation of Rac protein signal transduction | negative regulation of cell-substrate adhesion | glial cell differentiation | organic anion transport | phosphorylation | inositol lipid-mediated signaling | positive regulation of neuron death | regulation of GTPase activity | regulation of apoptotic signaling pathway | regulation of cyclase activity | endocrine system development | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | chordate embryonic development | striated muscle tissue development | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | eye morphogenesis | sympathetic nervous system development | regulation of neuron apoptotic process | metanephros development | astrocyte differentiation | regulation of protein metabolic process | positive regulation of signal transduction | heart development | negative regulation of stem cell proliferation | limbic system development | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | negative regulation of MAP kinase activity | renal system development | cerebral cortex development | apoptotic signaling pathway | amino acid transport | smooth muscle tissue development | positive regulation of molecular function | regulation of nucleocytoplasmic transport | gamma-aminobutyric acid transport | negative regulation of epithelial cell proliferation | protein metabolic process | regulation of fibroblast proliferation | regulation of establishment of protein localization | gland development | artery morphogenesis | regulation of protein import into nucleus | visual behavior | regulation of hemopoiesis | regulation of kinase activity | response to wounding | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | positive regulation of neuron apoptotic process | phosphatidylinositol 3-kinase signaling | anatomical structure development | Schwann cell development | cell surface receptor signaling pathway | regulation of neural precursor cell proliferation | metabolic process | regulation of bone resorption | adrenal gland development | regulation of tissue remodeling | negative regulation of endothelial cell proliferation | regulation of secretion | behavior | positive regulation of cell death | organic substance metabolic process | cell death | animal organ development | regulation of endothelial cell proliferation | forebrain development | pallium development | negative regulation of cellular protein metabolic process | negative regulation of small GTPase mediated signal transduction | negative regulation of cellular component movement | negative regulation of Ras protein signal transduction | positive regulation of programmed cell death | response to heat | regulation of phosphate metabolic process | cytoskeleton organization | regulation of adenylate cyclase activity | camera-type eye development | negative regulation of protein metabolic process | regulation of epithelial cell migration | regulation of osteoclast differentiation | regulation of glial cell differentiation | regulation of cell communication | regulation of blood vessel endothelial cell migration | regulation of gliogenesis | negative regulation of molecular function | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | glial cell development | cell development | collagen fibril organization | regulation of epithelial cell proliferation | negative regulation of fibroblast proliferation | cellular protein metabolic process | enzyme regulator activity | carboxylic acid transport | regulation of Ras protein signal transduction | anatomical structure morphogenesis | camera-type eye morphogenesis | synaptic transmission, GABAergic | glutamate secretion | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | negative regulation of glial cell differentiation | cellular protein modification process | tube development | regulation of transport | negative regulation of cell proliferation | negative regulation of neural precursor cell proliferation | negative regulation of vasculature development | Ras protein signal transduction | neurotransmitter transport | signal release | negative regulation of synaptic transmission | central nervous system development | spinal cord development | ossification | regulation of synaptic plasticity | osteoblast differentiation | ion transport | cellular metabolic process | regulation of protein localization | regulation of astrocyte differentiation | regulation of cell death | negative regulation of oligodendrocyte differentiation | negative regulation of cell development | circulatory system development | negative regulation of locomotion | negative regulation of myeloid leukocyte differentiation | negative regulation of cell differentiation | myelination in peripheral nervous system | positive regulation of apoptotic signaling pathway | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | regulation of neurotransmitter secretion | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | dendritic tree | presynapse | cell projection | membrane-bounded organelle | nucleus | organelle | axon | membrane-enclosed lumen | intracellular