QuickView for OGDH;jsessionid=CE131E3C0A0C5E4B100D6139038885D6;jsessionid=C51CCA97271579B24EFC9C29A97B8299 (gene)
- Gene Symbol:
- KGD1
Saccharomyces cerevisiae - Full name:
- Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
- Synonyms:
- KGD1, OGD1, YIL125W
- Genomic Location:
- Chr IX: 122689-125733
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
ATF_01 , CREB_01 , CREBP1CJUN_01 , CREB_Q2 , CREB_Q4 , ATF_B , E2F1_Q4 , ATF4_Q2 , ATF1_Q6 , CREB_Q4_01
GO Molecular Function
thiamine pyrophosphate binding | cofactor binding | cation binding | vitamin binding | coenzyme binding | catalytic activity | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | anion binding | ion binding | organic cyclic compound binding | oxoglutarate dehydrogenase (succinyl-transferring) activity | heterocyclic compound binding | oxidoreductase activity | small molecule binding
GO Biological Process
tricarboxylic acid cycle | generation of precursor metabolites and energy | aerobic respiration | cellular process | dicarboxylic acid metabolic process | cellular respiration | cofactor metabolic process | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | antibiotic metabolic process | small molecule metabolic process | 2-oxoglutarate metabolic process | drug metabolic process | carboxylic acid metabolic process | tricarboxylic acid metabolic process | metabolic process | oxidation-reduction process | citrate metabolic process | organic substance metabolic process | oxoglutarate dehydrogenase (succinyl-transferring) activity | organic acid metabolic process | energy derivation by oxidation of organic compounds | cellular metabolic process | oxidoreductase activity
GO Cellular Component
mitochondrial matrix | intracellular membrane-bounded organelle | catalytic complex | cell | oxidoreductase complex | mitochondrial nucleoid | mitochondrial alpha-ketoglutarate dehydrogenase complex | cytoplasm | nucleoid | oxoglutarate dehydrogenase complex | intracellular organelle | protein-containing complex | transferase complex | mitochondrion | membrane-bounded organelle | organelle | tricarboxylic acid cycle enzyme complex | membrane-enclosed lumen | cytosol | intracellular | mitochondrial oxoglutarate dehydrogenase complex
