QuickView for OPTN;jsessionid=005971FBE9928DAC8897112ECFE42B2E;jsessionid=B74A72D802DDDACFBAB88941AF5E7C46;jsessionid=6912787DDA4D4C6D1953247C1FD55B8E;jsessionid=2C6E80B592724DD461924DE6B3F5D20F (gene)
- Gene Symbol:
- OPTN
Bos taurus - Full name:
- optineurin
- Synonyms:
- MGC128158
- Genomic Location:
- Chr 13: 27379164-27418033
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
GTPase binding | enzyme binding | Ras GTPase binding | protein binding, bridging | identical protein binding | molecular adaptor activity | protein binding | small GTPase binding | Rab GTPase binding | protein C-terminus binding
GO Biological Process
positive regulation of cellular component organization | protein localization to cell periphery | defense response to other organism | establishment of localization | regulation of autophagy | negative regulation of cellular process | defense response | regulation of organelle organization | defense response to Gram-negative bacterium | cellular process | localization | protein transport | negative regulation of signaling | parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | macromolecule localization | negative regulation of cellular metabolic process | Golgi to plasma membrane transport | regulation of cellular process | regulation of metabolic process | catabolic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular response to topologically incorrect protein | positive regulation of autophagy of mitochondrion | response to stimulus | response to stress | establishment of protein localization to plasma membrane | negative regulation of receptor recycling | cellular localization | positive regulation of mitophagy in response to mitochondrial depolarization | regulation of macroautophagy | negative regulation of metabolic process | positive regulation of mitochondrion organization | response to external biotic stimulus | regulation of signal transduction | positive regulation of organelle organization | protein localization to plasma membrane | post-Golgi vesicle-mediated transport | protein localization to membrane | organic substance transport | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | peptide transport | vesicle-mediated transport | protein localization to organelle | autophagy | regulation of mitochondrion organization | response to bacterium | regulation of cellular metabolic process | defense response to bacterium | Golgi vesicle transport | regulation of autophagy of mitochondrion | establishment of protein localization to membrane | protein localization to Golgi apparatus | response to organic substance | positive regulation of xenophagy | Golgi to plasma membrane protein transport | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | cellular protein localization | amide transport | positive regulation of autophagy | establishment of protein localization | positive regulation of macroautophagy | regulation of cell communication | response to mitochondrial depolarisation | negative regulation of signal transduction | protein localization | response to unfolded protein | cellular macromolecule localization | response to biotic stimulus | positive regulation of mitophagy | regulation of receptor recycling | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of I-kappaB kinase/NF-kappaB signaling | regulation of cellular component organization | response to other organism | regulation of signaling
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | perinuclear region of cytoplasm | membrane-bounded organelle | organelle | trans-Golgi network | cytosol | intracellular
