QuickView for ORM1;jsessionid=AFDC245D9FA37C5D599DBA36E75C992B;jsessionid=DAA5DAA125567E4018A858CDFF0C15E0;jsessionid=7A1306F6CB1C9E5AD26262987D2978C9;jsessionid=727453485035B5C3F7A1B1E11365B851 (gene)
- Gene Symbol:
- ORM1
Homo sapiens - Full name:
- orosomucoid 1
- Synonyms:
- AGP-A, AGP1, HEL-S-153w, ORM, alpha-1-acid glycoprotein 1, AGP 1, OMD 1, epididymis secretory sperm binding protein Li 153w
- Genomic Location:
- Chr 9: 116125157-116128578
- Description:
-
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Cytogenetic Map:
-
9q32
GO Molecular Function
GO Biological Process
regulation of interleukin-1 beta production | exocytosis | neutrophil activation | regulation of localization | establishment of localization | regulation of immune system process | platelet degranulation | defense response | positive regulation of interleukin-1 beta secretion | positive regulation of protein secretion | cellular process | secretion | leukocyte degranulation | localization | regulation of cellular process | leukocyte activation | negative regulation of tumor necrosis factor production | positive regulation of tumor necrosis factor production | regulation of peptide secretion | response to stimulus | positive regulation of interleukin-1 beta production | neutrophil degranulation | response to stress | negative regulation of tumor necrosis factor superfamily cytokine production | leukocyte activation involved in immune response | secretion by cell | positive regulation of cytokine secretion | regulation of protein transport | regulation of peptide transport | positive regulation of peptide secretion | negative regulation of interleukin-6 production | positive regulation of tumor necrosis factor secretion | leukocyte mediated immunity | positive regulation of secretion | negative regulation of cytokine production | vesicle-mediated transport | acute-phase response | regulated exocytosis | positive regulation of interleukin-1 secretion | regulation of tumor necrosis factor production | regulation of interleukin-1 production | positive regulation of interleukin-1 production | inflammatory response | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | positive regulation of establishment of protein localization | positive regulation of transport | regulation of cytokine secretion | regulation of establishment of protein localization | regulation of interleukin-1 beta secretion | regulation of secretion | immune response | regulation of protein secretion | regulation of tumor necrosis factor secretion | positive regulation of cytokine production | cell activation | positive regulation of protein transport | regulation of cytokine production | regulation of transport | neutrophil mediated immunity | acute inflammatory response | immune system process | regulation of protein localization | regulation of interleukin-6 production
GO Cellular Component
secretory granule | extracellular matrix | tertiary granule | cytoplasmic vesicle | cell | cytoplasmic vesicle lumen | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | platelet alpha granule | secretory vesicle | endomembrane system | vesicle | extracellular exosome | specific granule | extracellular region | membrane-bounded organelle | extracellular vesicle | specific granule lumen | organelle | extracellular space | tertiary granule lumen | membrane-enclosed lumen | secretory granule lumen | blood microparticle | intracellular vesicle | intracellular | platelet alpha granule lumen | vesicle lumen
