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QuickView for P4HTM;jsessionid=E5FAD69DFBA8D4AC818F15CB79155DA4;jsessionid=A136560E3C97AB192E3689F3D41893C0;jsessionid=8133993863B75B7F3807A421A3B7B6FB (gene)


Gene Symbol:
P4htm Mus musculus Mus musculus
Full name:
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Synonyms:
4933406E20Rik, AI853847, BB128974, HIF-PH4, HPH-4, P4H-TM, Ph-4, transmembrane prolyl 4-hydroxylase, HIF-prolyl hydroxylase 4, hypoxia-inducible factor prolyl hydroxylase 4
Genomic Location:
Chr 9: 108481157-108499931
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

cofactor binding | cation binding | L-ascorbic acid binding | carboxylic acid binding | procollagen-proline 4-dioxygenase activity | vitamin binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | iron ion binding | coenzyme binding | peptidyl-proline dioxygenase activity | monosaccharide binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | anion binding | peptidyl-proline 4-dioxygenase activity | ion binding | carbohydrate binding | dioxygenase activity | transition metal ion binding | calcium ion binding | organic acid binding | metal ion binding | oxidoreductase activity | small molecule binding

GO Biological Process

peptidyl-amino acid modification | regulation of immune system process | cellular process | peptidyl-proline modification | regulation of myeloid cell differentiation | regulation of cell differentiation | cellular amino acid metabolic process | regulation of cellular process | procollagen-proline 4-dioxygenase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | peptidyl-proline hydroxylation | peptidyl-proline dioxygenase activity | protein modification process | macromolecule modification | nitrogen compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 4-hydroxyproline metabolic process | peptidyl-proline hydroxylation to 4-hydroxy-L-proline | peptidyl-proline 4-dioxygenase activity | small molecule metabolic process | protein hydroxylation | carboxylic acid metabolic process | protein metabolic process | regulation of hemopoiesis | metabolic process | oxidation-reduction process | regulation of erythrocyte differentiation | organic substance metabolic process | dioxygenase activity | organic acid metabolic process | cellular protein metabolic process | regulation of developmental process | cellular protein modification process | cellular modified amino acid metabolic process | cellular metabolic process | oxidoreductase activity | macromolecule metabolic process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | endomembrane system | membrane-bounded organelle | organelle | intracellular | membrane