QuickView for PATJ;jsessionid=549282AE26BAAD24FD6D01AB2ACA3207;jsessionid=5C708F7444AB34ED39A9F05B76136750;jsessionid=495FECAC331E5B8199FCDC27D2D20EA6;jsessionid=5126B5CC95AB10857C094061B291FDCA (gene)

Gene Symbol:

PATJ Homo sapiens

Full name:

PATJ, crumbs cell polarity complex component

Synonyms:

Cipp, INADL, InaD-like, hINADL, inaD-like protein, PALS1-associated tight junction protein, PDZ domain protein, channel-interacting PDZ domain protein, inactivation no after-potential D-like protein, inactivation-no-afterpotential D-like, protein associated to tight junctions

Genomic Location:

Chr 1: 61980737-62402180

Description:

This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein...

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This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT1_02 ,  GGGCGGR_SP1_Q6 ,  MGGAAGTG_GABP_B ,  TTGTTT_FOXO4_01

Cytogenetic Map:

1p31.3

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