QuickView for PAWR;jsessionid=5DEFB28AA6506D852E208E7810A68700;jsessionid=DB94B51C4AD354B402F533BA5C5AF599;jsessionid=371215678D57385CF036A1F1E834301B (gene)
- Gene Symbol:
- Pawr
Rattus norvegicus - Full name:
- pro-apoptotic WT1 regulator
- Synonyms:
- Par-4, Par4, PRKC apoptosis WT1 regulator protein, PRKC, apoptosis, WT1, regulator, Prostate apoptosis response protein 4, par-4 induced by effectors of apoptosis, prostate apoptosis response 4 protein, transcriptional repressor Par-4-like protein PAWR
- Genomic Location:
- Chr 7: 47040162-47119613
- Description:
-
expression is induced by apoptosis effector ionomycin; may play a role in apoptosis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Danio rerio , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
actin binding | kinase binding | protein phosphatase 1 binding | protein kinase binding | enzyme binding | protein domain specific binding | protein kinase C binding | cytoskeletal protein binding | protein binding | protein phosphatase binding | leucine zipper domain binding | LRR domain binding | phosphatase binding
GO Biological Process
RNA metabolic process | negative regulation of leukocyte activation | response to extracellular stimulus | positive regulation of action potential | regulation of hydrogen peroxide-induced cell death | regulation of muscle system process | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | regulation of cysteine-type endopeptidase activity | regulation of dephosphorylation | positive regulation of leukocyte adhesion to vascular endothelial cell | response to nutrient levels | negative regulation of immune system process | positive regulation of cell aging | actin filament-based process | detection of stimulus | regulation of transmission of nerve impulse | response to cytokine | response to interleukin-1 | interleukin-2 biosynthetic process | regulation of cellular response to oxidative stress | regulation of response to oxidative stress | positive regulation of leukocyte tethering or rolling | regulation of B cell activation | response to lipopolysaccharide | calcium ion transmembrane import into cytosol | positive regulation of apoptotic process | proteolysis | cytosolic calcium ion transport | regulation of localization | actin filament bundle organization | regulation of programmed cell death | regulation of cell aging | actin cytoskeleton organization | establishment of localization | calcium ion import into cytosol | regulation of immune system process | response to hormone | positive regulation of phosphoprotein phosphatase activity | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | positive regulation of developmental process | protein processing | regulation of phosphatase activity | negative regulation of RNA biosynthetic process | response to metal ion | detection of mechanical stimulus involved in sensory perception | cellular response to extracellular stimulus | regulation of smooth muscle contraction | negative regulation of B cell proliferation | cellular chemical homeostasis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | sensory perception of mechanical stimulus | regulation of neuron death | positive regulation of dephosphorylation | calcium ion import | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | positive regulation of glycoprotein biosynthetic process | calcium ion import across plasma membrane | regulation of cell motility | localization | cellular homeostasis | zymogen activation | negative regulation of signaling | metal ion transport | response to estradiol | negative regulation of T cell receptor signaling pathway | positive regulation of hindgut contraction | regulation of digestive system process | negative regulation of nucleic acid-templated transcription | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of T cell proliferation | response to inorganic substance | establishment of localization in cell | negative regulation of cellular metabolic process | regulation of T cell receptor signaling pathway | regulation of neurological system process | regulation of immune response | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | positive regulation of neutrophil migration | regulation of cytosolic calcium ion concentration | regulation of relaxation of muscle | negative regulation of mononuclear cell proliferation | regulation of cellular extravasation | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | calcium ion homeostasis | calcium ion transport into cytosol | response to stimulus | regulation of glycoprotein biosynthetic process | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of peptidase activity | negative regulation of cell adhesion | positive regulation of hydrogen peroxide-mediated programmed cell death | response to stress | negative regulation of lymphocyte activation | cellular response to vitamin | cellular nitrogen compound biosynthetic process | regulation of response to drug | regulation of cell proliferation | positive regulation of cell-cell adhesion | positive regulation of cysteine-type endopeptidase activity | sensory perception of temperature stimulus | positive regulation of amyloid precursor protein biosynthetic process | programmed cell death | positive regulation of phosphatase activity | supramolecular fiber organization | cellular localization | divalent metal ion transport | response to temperature stimulus | positive regulation of proteolysis | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | interleukin-2 production | negative regulation of transport | cellular response to organic cyclic compound | negative regulation of metabolic process | cellular component assembly | positive regulation of response to oxidative stress | regulation of cell adhesion | cellular biosynthetic process | response to iron ion | positive regulation of protein dephosphorylation | metal ion homeostasis | detection of temperature stimulus involved in sensory perception | regulation of nucleic acid-templated transcription | regulation of membrane potential | regulation of cellular response to stress | detection of abiotic stimulus | apoptotic process | cellular response to hormone stimulus | response to external biotic stimulus | cellular response to nutrient levels | nitrogen compound metabolic process | regulation of signal transduction | regulation of peptidase activity | calcium ion transmembrane transport | positive regulation of neutrophil extravasation | actin filament organization | response to follicle-stimulating hormone | response to vitamin E | regulation of muscle contraction | regulation of catalytic activity | ion transmembrane transport | regulation of T cell activation | detection of mechanical stimulus involved in sensory perception of pain | regulation of gene expression | response to lipid | nervous system process | regulation of neutrophil extravasation | cellular response to gonadotropin stimulus | positive regulation of cellular metabolic process | positive regulation of cellular response to oxidative stress | regulation of lymphocyte activation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | regulation of cell migration | regulation of neuronal action potential | regulation of cellular component movement | regulation of transcription by RNA polymerase II | response to nutrient | positive regulation of digestive system process | actin filament bundle assembly | positive regulation of hydrolase activity | positive regulation of cell migration | cellular response to cytokine stimulus | response to iron(II) ion | biosynthetic process | sensory perception of pain | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | negative regulation of ion transport | positive regulation of endopeptidase activity | positive regulation of neuron death | protein maturation | detection of temperature stimulus involved in sensory perception of pain | cation homeostasis | regulation of leukocyte migration | positive regulation of cellular extravasation | regulation of cellular response to drug | response to bacterium | negative regulation of cell-cell adhesion | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of smooth muscle contraction | positive regulation of response to drug | regulation of neuron apoptotic process | negative regulation of cell activation | negative regulation of calcium ion transport | regulation of protein metabolic process | cellular calcium ion homeostasis | homeostatic process | regulation of locomotion | positive regulation of oxidative stress-induced cell death | regulation of RNA metabolic process | positive regulation of hydrogen peroxide-induced cell death | apoptotic signaling pathway | negative regulation of B cell activation | positive regulation of molecular function | cation transmembrane transport | cytokine production | protein metabolic process | cellular response to nutrient | regulation of fibroblast proliferation | positive regulation of protein modification process | cellular response to vitamin E | response to organic substance | positive regulation of transmission of nerve impulse | regulation of protein dephosphorylation | response to wounding | response to mechanical stimulus | import into cell | detection of stimulus involved in sensory perception | regulation of response to reactive oxygen species | positive regulation of neuron apoptotic process | metabolic process | regulation of neutrophil migration | negative regulation of leukocyte proliferation | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | chemical homeostasis | calcium ion transport | positive regulation of cell death | nucleobase-containing compound metabolic process | positive regulation of muscle contraction | regulation of amyloid precursor protein biosynthetic process | organic substance metabolic process | cell death | response to vitamin | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | regulation of cell activation | positive regulation of leukocyte migration | positive regulation of programmed cell death | ion homeostasis | regulation of phosphate metabolic process | cytoskeleton organization | inorganic cation transmembrane transport | negative regulation of calcium ion import | detection of mechanical stimulus | positive regulation of glycoprotein metabolic process | transcription, DNA-templated | response to gonadotropin | cellular response to follicle-stimulating hormone stimulus | regulation of hindgut contraction | sensory perception | positive regulation of cellular response to drug | regulation of action potential | cellular response to estradiol stimulus | regulation of calcium ion import | regulation of cell communication | negative regulation of signal transduction | transmembrane transport | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of T cell proliferation | negative regulation of fibroblast proliferation | regulation of endopeptidase activity | cation transport | cellular macromolecule biosynthetic process | response to biotic stimulus | regulation of developmental process | regulation of ion transport | cytokine biosynthetic process | regulation of phosphoprotein phosphatase activity | positive regulation of cellular senescence | organelle organization | cellular response to interleukin-1 | regulation of calcium ion transport | positive regulation of neuronal action potential | inorganic cation import across plasma membrane | detection of temperature stimulus | negative regulation of transcription by RNA polymerase II | regulation of transport | regulation of B cell proliferation | negative regulation of cell proliferation | regulation of cell-cell adhesion | cellular metal ion homeostasis | cytokine metabolic process | heterocycle metabolic process | positive regulation of metabolic process | ion transport | negative regulation of lymphocyte proliferation | positive regulation of relaxation of smooth muscle | cellular metabolic process | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | divalent inorganic cation homeostasis | positive regulation of leukocyte cell-cell adhesion | activation of cysteine-type endopeptidase activity | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | regulation of cellular senescence | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | chromosome | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | cell body | cell | nuclear lumen | neuronal cell body | cytoplasm | intracellular organelle | actin cytoskeleton | cell projection | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | axon | membrane-enclosed lumen | nuclear chromatin | actin filament | cytoskeleton | intracellular | supramolecular complex
