QuickView for PCLO;jsessionid=BD1E019C2039AB0E165445940DE6E388;jsessionid=21D2E4B1A2918AA1241AD1F8E0E86BB6;jsessionid=72C3F4180CC39DFD16D66B5A2C6D76C2 (gene)
- Gene Symbol:
- Pclo
Rattus norvegicus - Full name:
- piccolo (presynaptic cytomatrix protein)
- Synonyms:
- aczonin, protein piccolo, multidomain presynaptic cytomatrix protein Piccolo, presynaptic cytomatrix protein
- Genomic Location:
- Chr 4: 15911051-16269090
- Description:
-
presynaptic low-affinity Ca(2+) sensor; may be involved in the assembly and function of presynaptic active zones
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus , Gallus gallus
- External Links:
- Entrez Gene
GO Molecular Function
transcription corepressor binding | cation binding | lipid binding | phospholipid binding | anion binding | ion binding | protein binding | transcription factor binding | calcium ion binding | transcription cofactor binding | calcium-dependent phospholipid binding | metal ion binding | profilin binding
GO Biological Process
synaptic vesicle exocytosis | exocytosis | neurotransmitter secretion | intracellular signal transduction | regulation of localization | hormone secretion | establishment of localization | nervous system development | intracellular transport | cellular process | secretion | peptide hormone secretion | establishment of organelle localization | localization | protein transport | chemical synaptic transmission | synapse assembly | macromolecule localization | establishment of localization in cell | regulation of cellular process | organelle localization | cellular component organization | presynapse to nucleus signaling pathway | response to stimulus | cellular localization | secretion by cell | cellular component assembly | vesicle targeting | cell-cell signaling | insulin secretion | regulation of neurotransmitter levels | synaptic vesicle cycle | system development | multicellular organism development | regulation of hormone levels | organic substance transport | synaptic signaling | peptide transport | vesicle-mediated transport | synapse organization | second-messenger-mediated signaling | establishment of vesicle localization | regulated exocytosis | protein localization to synapse | peptide secretion | cell communication | cyclic-nucleotide-mediated signaling | cAMP-mediated signaling | regulation of exocytosis | anatomical structure development | amide transport | regulation of vesicle-mediated transport | calcium ion regulated exocytosis | regulation of secretion | hormone transport | cytoskeleton organization | synaptic vesicle targeting | establishment of protein localization | signaling | synaptic vesicle localization | protein localization | developmental process | organelle organization | regulation of transport | neurotransmitter transport | signal release | vesicle localization | synaptic vesicle transport | protein secretion | signal transduction | multicellular organismal process
GO Cellular Component
presynaptic active zone cytoplasmic component | cytoskeleton of presynaptic active zone | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | neuromuscular junction | cytoplasmic vesicle | cell body | cell | neuronal cell body | distal axon | rod spherule | terminal bouton | cytoplasm | cortical cytoskeleton | intracellular organelle | dendritic tree | presynapse | Golgi apparatus | cell projection | endomembrane system | postsynapse | vesicle | transport vesicle | presynaptic cytoskeleton | perinuclear region of cytoplasm | postsynaptic density | cone cell pedicle | asymmetric synapse | cytoplasmic region | site of polarized growth | cell cortex region | cell cortex | membrane-bounded organelle | organelle | postsynaptic specialization | inhibitory synapse | axon terminus | presynaptic active zone | cell periphery | axon | trans-Golgi network | growth cone | neuron projection terminus | ribbon synapse | intracellular vesicle | cytoskeleton | intracellular | cell junction
