QuickView for PDE10A;jsessionid=8F605E84A4D2653566F7019E6E54FE1C;jsessionid=982D8454D2698E7D6D2307FB6D096249;jsessionid=D5323D1927408ADB56EBED6A3E637970;jsessionid=76D0B442F8346906BB93FC3D7FBF4AFE;jsessionid=B7FA40415A758B163651CB176A356447;jsessionid=F9EDC84B43D673B82E1E18C3CF176873;jsessionid=95482CF722E963A5C62C4D3ED896BB2B (gene)
- Gene Symbol:
- Pde10a
Mus musculus - Full name:
- phosphodiesterase 10A
- Synonyms:
- cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, PDE10A2 brain-specific isoform, dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase
- Genomic Location:
- Chr 17: 8994610-9179513
- Orthologs:
- Homo sapiens , Rattus norvegicus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
IK1_01 , PAX2_01 , ZF5_B , AP2REP_01 , RP58_01 , CTTTAAR_UNKNOWN , PTF1BETA_Q6 , EGR_Q6 , RNGTGGGC_UNKNOWN , WTTGKCTG_UNKNOWN
GO Molecular Function
guanyl ribonucleotide binding | cyclic nucleotide binding | cation binding | cAMP binding | ribonucleotide binding | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | cyclic-nucleotide phosphodiesterase activity | catalytic activity | anion binding | adenyl nucleotide binding | cGMP binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | 3',5'-cyclic-GMP phosphodiesterase activity | ion binding | organic cyclic compound binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | metal ion binding | heterocyclic compound binding | 3',5'-cyclic-nucleotide phosphodiesterase activity | guanyl nucleotide binding | small molecule binding
GO Biological Process
negative regulation of cGMP-mediated signaling | negative regulation of cellular process | cellular process | negative regulation of signaling | regulation of cellular process | response to stimulus | regulation of signal transduction | regulation of cGMP-mediated signaling | cell communication | regulation of cAMP-mediated signaling | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | regulation of protein kinase A signaling | regulation of cell communication | negative regulation of signal transduction | signaling | negative regulation of cAMP-mediated signaling | signal transduction | regulation of signaling
GO Cellular Component
somatodendritic compartment | cell body | cell | neuronal cell body | cytoplasm | perikaryon | intracellular | membrane
