QuickView for PDE10A;jsessionid=8F605E84A4D2653566F7019E6E54FE1C;jsessionid=EC504D8EE532F2F9318C1B9BFBE4DB37 (gene)
- Gene Symbol:
- Pde10a
Rattus norvegicus - Full name:
- phosphodiesterase 10A
- Synonyms:
- Pde10a3, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, testis-specific phosphodiesterase PDE10A2
- Genomic Location:
- Chr 1: 46392900-46589071
- Description:
-
has phosphodiesterase activity for cAMP and has cAMP inhibited activity for cGMP; activity is detected in brain striatum and testis
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
IK1_01 , PAX2_01 , ZF5_B , AP2REP_01 , RP58_01 , CTTTAAR_UNKNOWN , PTF1BETA_Q6 , EGR_Q6 , RNGTGGGC_UNKNOWN , WTTGKCTG_UNKNOWN
GO Molecular Function
guanyl ribonucleotide binding | cyclic nucleotide binding | cation binding | cAMP binding | ribonucleotide binding | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | cyclic-nucleotide phosphodiesterase activity | catalytic activity | anion binding | adenyl nucleotide binding | cGMP binding | purine nucleotide binding | hydrolase activity, acting on ester bonds | 3',5'-cyclic-GMP phosphodiesterase activity | ion binding | organic cyclic compound binding | phosphoric diester hydrolase activity | phosphoric ester hydrolase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | metal ion binding | heterocyclic compound binding | 3',5'-cyclic-nucleotide phosphodiesterase activity | guanyl nucleotide binding | small molecule binding
GO Biological Process
purine ribonucleotide metabolic process | negative regulation of cGMP-mediated signaling | nucleoside phosphate catabolic process | negative regulation of cellular process | organophosphate catabolic process | cellular process | organic substance catabolic process | nucleotide metabolic process | negative regulation of signaling | carbohydrate derivative catabolic process | ribose phosphate metabolic process | ribonucleotide metabolic process | regulation of cellular process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | nucleobase-containing compound catabolic process | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | cyclic nucleotide metabolic process | regulation of cGMP-mediated signaling | organophosphate metabolic process | small molecule metabolic process | cGMP metabolic process | cAMP catabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | nucleotide catabolic process | phosphate-containing compound metabolic process | cell communication | aromatic compound catabolic process | regulation of cAMP-mediated signaling | cyclic nucleotide catabolic process | cAMP metabolic process | cGMP catabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of protein kinase A signaling | organonitrogen compound catabolic process | regulation of cell communication | negative regulation of signal transduction | signaling | negative regulation of cAMP-mediated signaling | carbohydrate derivative metabolic process | heterocycle metabolic process | purine ribonucleotide catabolic process | cellular metabolic process | signal transduction | regulation of signaling | purine nucleotide catabolic process
GO Cellular Component
somatodendritic compartment | cell body | cell | neuronal cell body | cytoplasm | perikaryon | intracellular | membrane
