QuickView for PFKP;jsessionid=CEB8F09FF3F67689CDCB25840A84C861;jsessionid=64FA6FFB36941D9A06DB377784BAF1EC (gene)
- Gene Symbol:
- PFK1
Saccharomyces cerevisiae - Full name:
- Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
- Synonyms:
- PFK1, YGR240C
- Genomic Location:
- Chr VII: 970776-973739
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
GO Molecular Function
phosphofructokinase activity | cation binding | ribonucleotide binding | nucleotide binding | fructose-6-phosphate binding | carbohydrate derivative binding | monosaccharide binding | catalytic activity | ATP binding | anion binding | AMP binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | carbohydrate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | transferase activity | carbohydrate kinase activity | purine ribonucleotide binding | 6-phosphofructokinase activity | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
phosphofructokinase activity | purine ribonucleotide metabolic process | purine ribonucleoside monophosphate biosynthetic process | vacuolar acidification | nucleoside phosphate catabolic process | glycolytic process | glucose metabolic process | nicotinamide nucleotide biosynthetic process | generation of precursor metabolites and energy | organophosphate catabolic process | cellular chemical homeostasis | cellular process | organic substance catabolic process | cellular homeostasis | nucleotide metabolic process | NADH regeneration | ribose phosphate metabolic process | purine nucleotide biosynthetic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | carbohydrate catabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | pH reduction | purine nucleotide metabolic process | monocarboxylic acid metabolic process | intracellular pH reduction | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | carbohydrate derivative biosynthetic process | cofactor metabolic process | cellular component assembly | cellular biosynthetic process | nucleobase-containing compound catabolic process | nucleotide biosynthetic process | NADH metabolic process | ATP biosynthetic process | nitrogen compound metabolic process | coenzyme biosynthetic process | phosphorus metabolic process | ribonucleoside monophosphate biosynthetic process | protein complex oligomerization | NAD biosynthetic process | organophosphate metabolic process | nucleotide phosphorylation | cellular ion homeostasis | cofactor biosynthetic process | monosaccharide metabolic process | small molecule metabolic process | cellular carbohydrate metabolic process | nucleobase-containing small molecule metabolic process | carbohydrate phosphorylation | biosynthetic process | pyruvate metabolic process | aromatic compound biosynthetic process | phosphorylation | purine ribonucleotide biosynthetic process | carbohydrate metabolic process | nucleotide catabolic process | nucleoside triphosphate biosynthetic process | cation homeostasis | phosphate-containing compound metabolic process | cellular cation homeostasis | regulation of intracellular pH | aromatic compound catabolic process | homeostatic process | drug metabolic process | carboxylic acid metabolic process | pyridine nucleotide biosynthetic process | glycolytic process through glucose-6-phosphate | protein-containing complex assembly | nucleoside diphosphate metabolic process | regulation of pH | metabolic process | hexose metabolic process | oxidation-reduction process | chemical homeostasis | nucleobase-containing compound metabolic process | organic substance metabolic process | glycolytic process through fructose-6-phosphate | ion homeostasis | ATP generation from ADP | carbohydrate kinase activity | regulation of cellular pH | fructose 1,6-bisphosphate metabolic process | pyruvate biosynthetic process | ADP metabolic process | ribose phosphate biosynthetic process | cellular monovalent inorganic cation homeostasis | 6-phosphofructokinase activity | organic acid metabolic process | glucose catabolic process | kinase activity | nicotinamide nucleotide metabolic process | NAD metabolic process | carbohydrate derivative metabolic process | fructose 6-phosphate metabolic process | canonical glycolysis | heterocycle metabolic process | cellular metabolic process | ATP metabolic process | nucleoside diphosphate phosphorylation | nucleoside monophosphate biosynthetic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | organelle membrane | proton-transporting V-type ATPase complex | cell | organelle outer membrane | cytoplasm | intracellular organelle | vacuolar proton-transporting V-type ATPase complex | protein-containing complex | 6-phosphofructokinase complex | vacuole | transferase complex | mitochondrion | membrane-bounded organelle | organelle | mitochondrial outer membrane | mitochondrial envelope | outer membrane | proton-transporting two-sector ATPase complex | mitochondrial membrane | cytosol | intracellular | membrane | vacuolar membrane
