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QuickView for PLA2G1B;jsessionid=E711A888C1E471D1EFF07B858694791D;jsessionid=9158384EEFAAD4D791074CED4EF66627 (gene)


Gene Symbol:
Pla2g1b Mus musculus Mus musculus
Full name:
phospholipase A2, group IB, pancreas
Synonyms:
Pla2a, sPLA2IB, phospholipase A2, PLA2-Ib, group IB phospholipase A2, phosphatidylcholine 2-acylhydrolase 1B
Genomic Location:
Chr 5: 115916275-115924726
Orthologs:
Homo sapiens Rattus norvegicus C. elegans Macaca mulatta Bos taurus Canis lupus familiaris Danio rerio Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

calcium-dependent phospholipase A2 activity | cation binding | phospholipase activity | lipid binding | carboxylic ester hydrolase activity | signaling receptor binding | hydrolase activity | phospholipid binding | catalytic activity | anion binding | phospholipase A2 activity | hydrolase activity, acting on ester bonds | ion binding | lipase activity | protein binding | calcium ion binding | metal ion binding

GO Biological Process

positive regulation of immune response | long-chain fatty acid transport | positive regulation of macromolecule biosynthetic process | leukotriene biosynthetic process | leukotriene metabolic process | cell motility | regulation of cellular localization | intracellular signal transduction | regulation of localization | positive regulation of DNA-binding transcription factor activity | lipid transport | defense response to other organism | establishment of localization | regulation of immune system process | response to hormone | regulation of MAP kinase activity | positive regulation of fibroblast proliferation | defense response | organophosphate catabolic process | cellular chemical homeostasis | positive regulation of phosphate metabolic process | phospholipid metabolic process | positive regulation of cellular biosynthetic process | cellular process | secretion | organic substance catabolic process | monocarboxylic acid transport | regulation of glucose import | localization | cellular homeostasis | anion transport | positive regulation of protein kinase activity | macromolecule localization | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | granulocyte chemotaxis | response to peptide hormone | regulation of immune response | regulation of cellular process | regulation of metabolic process | catabolic process | regulation of cytosolic calcium ion concentration | interleukin-8 production | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | icosanoid biosynthetic process | cellular lipid metabolic process | calcium ion homeostasis | response to stimulus | acid secretion | monocarboxylic acid metabolic process | neutrophil chemotaxis | positive regulation of immune system process | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | response to peptide | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | cellular biosynthetic process | cell chemotaxis | activation of protein kinase activity | metal ion homeostasis | leukocyte migration | regulation of nucleic acid-templated transcription | locomotion | response to nitrogen compound | regulation of calcium ion transport into cytosol | cellular response to hormone stimulus | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | cell migration | antibacterial humoral response | cellular response to peptide hormone stimulus | regulation of MAPK cascade | phosphorus metabolic process | leukocyte mediated immunity | cellular response to insulin stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | lipid metabolic process | regulation of phosphorylation | arachidonic acid secretion | regulation of gene expression | fatty acid transport | organic substance transport | cellular response to peptide | organophosphate metabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | small molecule metabolic process | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | phospholipid catabolic process | organic acid transport | fatty acid biosynthetic process | biosynthetic process | regulation of cellular protein metabolic process | organic anion transport | lipid biosynthetic process | cation homeostasis | phosphate-containing compound metabolic process | response to bacterium | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | cellular lipid catabolic process | antimicrobial humoral immune response mediated by antimicrobial peptide | humoral immune response | regulation of protein metabolic process | positive regulation of signal transduction | leukocyte chemotaxis | cellular calcium ion homeostasis | defense response to bacterium | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | glycerolipid metabolic process | regulation of RNA metabolic process | positive regulation of transport | carboxylic acid metabolic process | positive regulation of molecular function | activation of MAPK activity | cytokine production | antimicrobial humoral response | regulation of fibroblast proliferation | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | response to insulin | metabolic process | lipid localization | regulation of RNA biosynthetic process | chemical homeostasis | immune response | lipid catabolic process | organic substance metabolic process | regulation of glucose transmembrane transport | positive regulation of ion transport | positive regulation of NF-kappaB transcription factor activity | phosphatidylcholine metabolic process | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | fatty acid metabolic process | positive regulation of MAPK cascade | icosanoid metabolic process | defense response to Gram-positive bacterium | regulation of cell communication | signaling | regulation of transcription, DNA-templated | organic acid metabolic process | positive regulation of phosphorylation | carboxylic acid transport | positive regulation of MAP kinase activity | positive regulation of calcium ion transport into cytosol | response to biotic stimulus | regulation of ion transport | glycerophospholipid metabolic process | regulation of calcium ion transport | mucosal immune response | regulation of transport | positive regulation of transcription, DNA-templated | innate immune response | positive regulation of nucleic acid-templated transcription | neutrophil mediated immunity | response to organonitrogen compound | cellular metal ion homeostasis | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | ion transport | immune system process | cellular metabolic process | cellular response to organic substance | neutrophil migration | chemotaxis | divalent inorganic cation homeostasis | innate immune response in mucosa | positive regulation of calcium ion transport | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

secretory granule | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | secretory vesicle | endomembrane system | vesicle | extracellular region | membrane-bounded organelle | organelle | extracellular space | cytosol | intracellular vesicle | cell surface | intracellular