QuickView for PLK1;jsessionid=79F262793D6031E626261D39DE822608;jsessionid=5C3223676C6B4A97C4242EED5EC8908A (gene)
- Gene Symbol:
- polo
D. melanogaster - Full name:
- CG12306 gene product from transcript CG12306-RA
- Synonyms:
- 0256/04, 1324/08, anon-WO0172774.3, CG12306, DmelCG12306, Dmel_CG12306, l(3)01673, l(3)77Aa, l(3)S025604, l(3)S132408, polo, POLO, POLO/PLK1
- Genomic Location:
- Chr 3L: 20303105-20306566
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
male germline ring canal formation | nucleus organization | actin filament-based process | extracellular structure organization | regulation of neurogenesis | developmental process involved in reproduction | regulation of cell development | organelle fusion | actin cytoskeleton organization | establishment of localization | negative regulation of neuroblast proliferation | negative regulation of cellular process | microtubule cytoskeleton organization | cell differentiation | male gamete generation | attachment of mitotic spindle microtubules to kinetochore | nervous system development | male meiotic nuclear division | oocyte fate commitment | neurogenesis | generation of neurons | intracellular transport | regulation of neuroblast proliferation | microtubule-based process | male meiosis cytokinesis | cellular process | establishment of organelle localization | localization | cytokinetic process | karyogamy | cytoskeleton-dependent cytokinesis | multicellular organismal reproductive process | macromolecule localization | microtubule organizing center organization | spindle midzone assembly | spindle assembly | establishment of localization in cell | tissue development | regulation of cell differentiation | gamete generation | regulation of cellular process | microtubule polymerization | meiotic cytokinesis | assembly of actomyosin apparatus involved in cytokinesis | organelle localization | cortical actin cytoskeleton organization | microtubule nucleation | epithelium development | cellular component organization | establishment of chromosome localization | female gamete generation | chromosome segregation | germ cell development | regulation of cell proliferation | protein serine/threonine kinase activity | intercellular bridge organization | supramolecular fiber organization | reproduction | cellular localization | astral microtubule organization | cellular component assembly | protein modification process | embryo development | macromolecule modification | organelle assembly | system development | nitrogen compound metabolic process | reproductive process | multicellular organism development | sister chromatid segregation | phosphorus metabolic process | oocyte differentiation | cell cycle | spindle assembly involved in female meiosis | pronuclear migration | regulation of stem cell proliferation | mitotic metaphase plate congression | pronuclear fusion | sperm aster formation | protein polymerization | germline ring canal formation | oogenesis | astral microtubule nucleation | meiotic spindle midzone assembly | cell division | metaphase plate congression | spindle assembly involved in female meiosis II | meiotic spindle organization | fertilization | cytokinesis | phosphorylation | actomyosin structure organization | cellular protein-containing complex assembly | meiosis II | protein phosphorylation | phosphate-containing compound metabolic process | nuclear chromosome segregation | nuclear migration | cytoplasmic microtubule organization | heart development | negative regulation of stem cell proliferation | single fertilization | spindle assembly involved in meiosis | female meiosis II | nucleus localization | multicellular organism reproduction | protein-containing complex assembly | protein metabolic process | centrosome cycle | embryonic heart tube development | anatomical structure development | mitotic cell cycle | regulation of neural precursor cell proliferation | nuclear division | metabolic process | cell fate commitment | embryonic organ development | cellular protein localization | protein kinase activity | organic substance metabolic process | animal organ development | cytoskeleton organization | mitotic nuclear division | microtubule polymerization or depolymerization | attachment of spindle microtubules to kinetochore | meiotic cell cycle | cell development | protein localization | cellular protein metabolic process | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | organelle organization | spermatogenesis | cellular protein modification process | cortical cytoskeleton organization | tube development | negative regulation of cell proliferation | negative regulation of neural precursor cell proliferation | actomyosin contractile ring assembly | chromosome organization | cellular metabolic process | negative regulation of cell development | circulatory system development | spindle organization | mitotic sister chromatid segregation | sexual reproduction | negative regulation of cell differentiation | female meiotic nuclear division | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
mitotic spindle midzone | supramolecular fiber | chromosome | centriole | intracellular membrane-bounded organelle | microtubule organizing center | chromosome, centromeric region | condensed chromosome outer kinetochore | condensed chromosome, centromeric region | cell | kinetochore | microtubule | cytoplasm | spindle | intracellular organelle | kinetochore microtubule | centrosome | protein-containing complex | endomembrane system | nuclear envelope | midbody | condensed chromosome kinetochore | microtubule cytoskeleton | spindle pole | spindle microtubule | spindle midzone | membrane-bounded organelle | nucleus | organelle | cytoskeleton | intracellular | mitotic spindle | supramolecular complex | condensed chromosome
