QuickView for PNP;jsessionid=F7A529ED35C1EA2A1DC56E6A6A54195C;jsessionid=D59E8177EF606076FDEB532F467EA8F3;jsessionid=FFC66E3CBC2165106ADB930FBCEBDFDA;jsessionid=17C5831C38135898798461F2A0E0B907 (gene)
- Gene Symbol:
- Pnp
Mus musculus - Full name:
- purine-nucleoside phosphorylase
- Synonyms:
- AL024301, AU015798, Np, Np-1, Np-2, Pnp1, purine nucleoside phosphorylase, inosine phosphorylase, inosine-guanosine phosphorylase, purine-nucleoside phosphorylase 1
- Genomic Location:
- Chr 14: 51564200-51573087
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Canis lupus familiaris , Bos taurus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
purine nucleobase binding | carbohydrate derivative binding | phosphate ion binding | catalytic activity | anion binding | purine-nucleoside phosphorylase activity | transferase activity, transferring glycosyl groups | ion binding | organic cyclic compound binding | transferase activity, transferring pentosyl groups | transferase activity | nucleoside binding | drug binding | heterocyclic compound binding | small molecule binding
GO Biological Process
positive regulation of immune response | positive regulation of cell killing | regulation of T cell mediated immunity | purine ribonucleotide metabolic process | response to radiation | regulation of B cell activation | intracellular signal transduction | regulation of programmed cell death | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of lymphocyte activation | urate biosynthetic process | regulation of T cell differentiation | regulation of T cell mediated cytotoxicity | deoxyribonucleoside triphosphate metabolic process | intrinsic apoptotic signaling pathway in response to DNA damage | regulation of leukocyte mediated cytotoxicity | positive regulation of cell adhesion | nucleoside catabolic process | regulation of DNA repair | positive regulation of T cell differentiation | cellular process | organic substance catabolic process | deoxyinosine catabolic process | nucleotide metabolic process | positive regulation of immune effector process | positive regulation of adaptive immune response | carbohydrate derivative catabolic process | ribose phosphate metabolic process | purine nucleotide biosynthetic process | guanosine catabolic process | negative regulation of apoptotic process | nucleoside triphosphate metabolic process | positive regulation of nitrogen compound metabolic process | ribonucleotide metabolic process | purine nucleoside catabolic process | deoxyribonucleoside catabolic process | regulation of cell differentiation | intrinsic apoptotic signaling pathway | regulation of lymphocyte apoptotic process | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | positive regulation of response to DNA damage stimulus | response to stimulus | purine nucleotide metabolic process | negative regulation of T cell apoptotic process | positive regulation of immune system process | response to stress | positive regulation of lymphocyte proliferation | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | positive regulation of cell-cell adhesion | programmed cell death | positive regulation of cell activation | cellular nitrogen compound metabolic process | positive regulation of T cell activation | apoptotic mitochondrial changes | carbohydrate derivative biosynthetic process | regulation of cell adhesion | cellular biosynthetic process | purine nucleoside metabolic process | mitochondrion organization | nucleobase-containing compound catabolic process | positive regulation of B cell differentiation | urate metabolic process | inosine catabolic process | nucleotide biosynthetic process | regulation of lymphocyte differentiation | regulation of cellular response to stress | apoptotic process | positive regulation of mononuclear cell proliferation | nitrogen compound metabolic process | positive regulation of lymphocyte differentiation | phosphorus metabolic process | purine ribonucleoside catabolic process | cellular response to DNA damage stimulus | regulation of T cell activation | positive regulation of alpha-beta T cell differentiation | cellular response to stress | organophosphate metabolic process | nucleoside metabolic process | positive regulation of cellular metabolic process | regulation of lymphocyte activation | deoxyribonucleotide metabolic process | nucleobase-containing small molecule catabolic process | purine deoxyribonucleoside metabolic process | negative regulation of lymphocyte apoptotic process | regulation of nitrogen compound metabolic process | small molecule metabolic process | deoxyguanosine catabolic process | positive regulation of cell differentiation | nucleobase-containing small molecule metabolic process | guanosine metabolic process | biosynthetic process | aromatic compound biosynthetic process | positive regulation of T cell proliferation | purine ribonucleotide biosynthetic process | nucleoside triphosphate biosynthetic process | response to gamma radiation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | GTP metabolic process | regulation of alpha-beta T cell differentiation | regulation of T cell apoptotic process | aromatic compound catabolic process | positive regulation of cell proliferation | positive regulation of B cell activation | apoptotic signaling pathway | regulation of hemopoiesis | metabolic process | regulation of adaptive immune response | positive regulation of leukocyte activation | negative regulation of programmed cell death | dGTP metabolic process | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of B cell differentiation | cell death | positive regulation of T cell mediated cytotoxicity | regulation of cell activation | positive regulation of T cell mediated immunity | organonitrogen compound catabolic process | signaling | ribose phosphate biosynthetic process | regulation of T cell proliferation | organic acid metabolic process | negative regulation of leukocyte apoptotic process | regulation of developmental process | positive regulation of DNA metabolic process | organelle organization | positive regulation of alpha-beta T cell activation | carbohydrate derivative metabolic process | regulation of cell-cell adhesion | positive regulation of leukocyte mediated cytotoxicity | heterocycle metabolic process | GTP biosynthetic process | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | negative regulation of cell death | positive regulation of leukocyte cell-cell adhesion | response to ionizing radiation | signal transduction | positive regulation of DNA repair
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | extracellular region | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
