QuickView for PP1;jsessionid=A1139A80A334F706921D407FAE1C49EF;jsessionid=16712A9EE2DE9822CA371534F40D7EC4 (gene)

Gene Symbol:

PPP1CB Homo sapiens

Full name:

protein phosphatase 1 catalytic subunit beta

Synonyms:

HEL-S-80p, NSLH2, PP-1B, PP1B, PP1beta, PPP1CD, serine/threonine-protein phosphatase PP1-beta catalytic subunit, epididymis secretory sperm binding protein Li 80p, protein phosphatase 1, catalytic subunit, beta isoform, protein phosphatase 1, catalytic subunit, beta isozyme, protein phosphatase 1, catalytic subunit, delta isoform, protein phosphatase 1-beta, protein phosphatase 1-delta

Genomic Location:

Chr 2: 28828118-28879310

Description:

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. ...

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The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RTAAACA_FREAC2_01 ,  FREAC7_01 ,  HNF3ALPHA_Q6 ,  CEBPA_01 ,  FOX_Q2 ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  HFH3_01 ,  ATGTCAC_MIR489 ,  AAAYWAACM_HFH4_01 ,  FOXD3_01 ,  HFH1_01 ,  TTTGTAG_MIR520D ,  CEBP_Q2_01 ,  HP1SITEFACTOR_Q6 ,  GTGCAAA_MIR507 ,  GGTGAAG_MIR412 ,  TGACCTY_ERR1_Q2 ,  CTTTGTA_MIR524 ,  GGGAGGRR_MAZ_Q6 ,  CEBP_Q2 ,  CEBPB_01 ,  TAATGTG_MIR323 ,  CATTTCA_MIR203 ,  FOXO3_01 ,  CEBP_01 ,  FREAC3_01 ,  RREB1_01 ,  CAGNYGKNAAA_UNKNOWN ,  TGCACTG_MIR148A_MIR152_MIR148B ,  HNF3_Q6 ,  ATTCTTT_MIR186 ,  HNF3B_01 ,  FOXJ2_01 ,  CEBPB_02 ,  FOXO1_01 ,  HFH4_01 ,  HFH8_01 ,  AATGTGA_MIR23A_MIR23B ,  TTGTTT_FOXO4_01 ,  IK3_01 ,  CTTTGT_LEF1_Q2 ,  AAAGGAT_MIR501 ,  CCATCCA_MIR432 ,  RCGCANGCGY_NRF1_Q6 ,  CACBINDINGPROTEIN_Q6 ,  P300_01 ,  HNF1_Q6 ,  HNF6_Q6 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-148 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-217 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-23 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-323 ,  Predicted Gene Targets for miR-340 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-542-3p ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-203 ,  Predicted Gene Targets for miR-363 ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

2p23.2

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