QuickView for PSMD2;jsessionid=40FD3424F9A84C12AEC5E5A38884A5DE;jsessionid=B671A4F5CC7A923F24EEAD25A55F91D9 (gene)
- Gene Symbol:
- RPN1
Saccharomyces cerevisiae - Full name:
- Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein?protein interactions
- Synonyms:
- HRD2, NAS1, Rpn1, RPN1, YHR027C
- Genomic Location:
- Chr VIII: 161723-164704
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFE2_01 , AP1_Q6 , ZF5_B , AP1_01 , NRF2_Q4 , AP1_Q6_01 , E2F1_Q3_01 , WGTTNNNNNAAA_UNKNOWN , YGCGYRCGC_UNKNOWN , TGANTCA_AP1_C
GO Molecular Function
hydrolase activity | molecular function regulator | catalytic activity | protein binding, bridging | molecular adaptor activity | protein binding | endopeptidase activity | enzyme regulator activity | peptidase activity
GO Biological Process
proteolysis | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | regulation of metabolic process | catabolic process | cellular protein catabolic process | proteasomal protein catabolic process | molecular function regulator | nitrogen compound metabolic process | regulation of catalytic activity | protein catabolic process | regulation of nitrogen compound metabolic process | regulation of protein metabolic process | proteasome-mediated ubiquitin-dependent protein catabolic process | protein metabolic process | cellular macromolecule catabolic process | metabolic process | regulation of protein catabolic process | organic substance metabolic process | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | endopeptidase activity | cellular protein metabolic process | enzyme regulator activity | cellular metabolic process | peptidase activity | modification-dependent protein catabolic process | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | proteasome regulatory particle | catalytic complex | cell | cytoplasm | proteasome complex | intracellular organelle | endoplasmic reticulum | protein-containing complex | proteasome storage granule | endomembrane system | proteasome regulatory particle, base subcomplex | membrane-bounded organelle | nucleus | organelle | cytosolic proteasome complex | cytosol | intracellular | proteasome accessory complex
