QuickView for PTK2;jsessionid=98C17EBE4781E0134398193CBA00DEC5;jsessionid=1481E88CFEFBEE6F455E600C032725EE;jsessionid=28DE2ACC5CC276F80AF52FA7C99E399B (gene)
- Gene Symbol:
- PTK2
Gallus gallus - Full name:
- PTK2 protein tyrosine kinase 2
- Synonyms:
- FAK, FRNK
- Genomic Location:
- Chr 2: 151344628-151466539
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Danio rerio , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AP4_01 , AACTTT_UNKNOWN , ETS1_B , CTGCAGY_UNKNOWN , CEBPGAMMA_Q6 , TEL2_Q6 , ICSBP_Q6 , ETS_Q4 , IRF_Q6 , AAGCCAT_MIR135A_MIR135B
GO Molecular Function
actin binding | kinase binding | calcium-dependent cysteine-type endopeptidase activity | protein kinase binding | enzyme binding | ribonucleotide binding | JUN kinase binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | cysteine-type peptidase activity | catalytic activity | protein domain specific binding | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | cysteine-type endopeptidase activity | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | non-membrane spanning protein tyrosine kinase activity | purine ribonucleotide binding | endopeptidase activity | adenyl ribonucleotide binding | drug binding | kinase activity | protease binding | heterocyclic compound binding | peptidase activity | small molecule binding | SH2 domain binding
GO Biological Process
negative regulation of phosphorylation | brain development | cell morphogenesis | regulation of muscle system process | positive regulation of locomotion | actin filament-based process | extracellular structure organization | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | positive regulation of adherens junction organization | regulation of synapse assembly | proteolysis | regulation of cell development | regulation of localization | morphogenesis of an epithelium | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | actin cytoskeleton organization | establishment of localization | regulation of autophagy | response to hormone | regulation of cell shape | neuron migration | negative regulation of cellular process | integrin-mediated signaling pathway | microtubule cytoskeleton organization | cell differentiation | signal complex assembly | negative regulation of organ growth | nervous system development | response to growth hormone | positive regulation of protein catabolic process | negative regulation of protein phosphorylation | epithelial cell migration | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | positive regulation of cellular component movement | generation of neurons | intracellular transport | microtubule-based process | blood vessel morphogenesis | cellular process | negative regulation of axonogenesis | establishment of organelle localization | regulation of cell motility | central nervous system neuron axonogenesis | localization | cell projection morphogenesis | forebrain cell migration | negative regulation of synapse organization | neuron development | negative regulation of developmental growth | central nervous system neuron differentiation | negative regulation of anoikis | epithelium migration | calcium-dependent cysteine-type endopeptidase activity | positive regulation of protein kinase activity | positive regulation of substrate-dependent cell migration, cell attachment to substrate | negative regulation of apoptotic process | regulation of proteolysis | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | forebrain neuron differentiation | regulation of neuron projection development | cellular response to growth hormone stimulus | establishment of localization in cell | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of binding | regulation of cell differentiation | positive regulation of cardiac muscle hypertrophy | regulation of protein kinase B signaling | peptidyl-tyrosine autophosphorylation | regulation of cellular process | regulation of osteoblast differentiation | regulation of apoptotic process | regulation of metabolic process | gliogenesis | organelle localization | epidermal growth factor receptor signaling pathway | positive regulation of cellular protein metabolic process | negative regulation of protein autophosphorylation | epithelium development | cellular response to organonitrogen compound | ephrin receptor signaling pathway | cellular component organization | negative regulation of cell morphogenesis involved in differentiation | response to transforming growth factor beta | positive regulation of protein binding | head development | positive regulation of cellular protein catabolic process | response to stimulus | vasculature development | cell morphogenesis involved in neuron differentiation | wound healing, spreading of cells | regulation of peptidyl-tyrosine phosphorylation | cerebral cortex radial glia guided migration | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | negative regulation of cell adhesion | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | endothelial cell migration | regulation of cell proliferation | negative regulation of neuron projection development | tube morphogenesis | response to peptide | response to muscle stretch | telencephalon cell migration | supramolecular fiber organization | positive regulation of proteolysis involved in cellular protein catabolic process | cellular localization | cardiovascular system development | positive regulation of proteolysis | extracellular matrix organization | ERBB signaling pathway | negative regulation of metabolic process | cellular component assembly | regulation of anoikis | protein modification process | regulation of synapse structure or activity | regulation of cell adhesion | response to pH | macromolecule modification | cysteine-type peptidase activity | positive regulation of cell-matrix adhesion | pyramidal neuron development | epiboly | blood vessel development | locomotion | response to nitrogen compound | central nervous system neuron development | cellular response to hormone stimulus | regulation of protein tyrosine kinase activity | positive regulation of cell junction assembly | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | negative regulation of phosphate metabolic process | regulation of adherens junction organization | multicellular organism development | cell migration | cellular response to peptide hormone stimulus | phosphorus metabolic process | actin filament organization | regulation of axonogenesis | positive regulation of protein kinase B signaling | regulation of catalytic activity | forebrain neuron development | regulation of phosphorylation | regulation of ossification | wound healing | telencephalon development | regulation of neuron differentiation | axon development | cellular response to peptide | regulation of protein autophosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of synapse organization | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | glial cell migration | regulation of cell-substrate adhesion | enzyme linked receptor protein signaling pathway | positive regulation of intracellular signal transduction | regulation of cellular component movement | morphogenesis of an epithelial sheet | axonogenesis | positive regulation of cell migration | regulation of cellular protein metabolic process | negative regulation of cell-substrate adhesion | angiogenesis | regulation of cell adhesion mediated by integrin | phosphorylation | cellular protein-containing complex assembly | cerebral cortex cell migration | protein phosphorylation | cell morphogenesis involved in differentiation | phosphate-containing compound metabolic process | negative regulation of autophagy | nuclear migration | negative regulation of cell-cell adhesion | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | pyramidal neuron differentiation | positive regulation of cell proliferation | regulation of protein phosphorylation | cysteine-type endopeptidase activity | regulation of locomotion | cerebral cortex development | protein tyrosine kinase activity | positive regulation of molecular function | cellular response to transforming growth factor beta stimulus | nucleus localization | neuron differentiation | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of cardiac muscle hypertrophy | positive regulation of focal adhesion assembly | positive regulation of protein modification process | regulation of growth | response to organic substance | negative regulation of cell projection organization | tissue morphogenesis | regulation of kinase activity | response to wounding | response to mechanical stimulus | regulation of intracellular signal transduction | regulation of focal adhesion assembly | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | metabolic process | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | negative regulation of programmed cell death | forebrain generation of neurons | protein kinase activity | neuron projection development | positive regulation of cellular component biogenesis | organic substance metabolic process | animal organ development | cerebral cortex radially oriented cell migration | forebrain development | negative regulation of neuron differentiation | positive regulation of cell-substrate adhesion | pallium development | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | regulation of phosphate metabolic process | cytoskeleton organization | positive regulation of binding | angiogenesis involved in wound healing | transforming growth factor beta receptor signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of protein metabolic process | regulation of epithelial cell migration | non-membrane spanning protein tyrosine kinase activity | regulation of cell communication | signaling | regulation of protein binding | endopeptidase activity | cell development | regulation of developmental growth | growth hormone receptor signaling pathway | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | cellular protein metabolic process | anatomical structure morphogenesis | regulation of organ growth | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | organelle organization | cellular protein modification process | tube development | regulation of cell junction assembly | regulation of cell-cell adhesion | response to organonitrogen compound | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | regulation of cell projection organization | cellular metabolic process | peptidase activity | ameboidal-type cell migration | cellular response to organic substance | regulation of cell death | positive regulation of cell motility | regulation of substrate adhesion-dependent cell spreading | negative regulation of cell death | negative regulation of cell development | circulatory system development | regulation of ubiquitin-dependent protein catabolic process | negative regulation of synapse assembly | negative regulation of cell differentiation | regulation of cellular component organization | pyramidal neuron migration | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | regulation of cell-matrix adhesion | cellular response to growth factor stimulus | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
dendritic spine | dendrite | intracellular membrane-bounded organelle | sarcolemma | synapse | apical plasma membrane | neuron projection | somatodendritic compartment | adherens junction | microtubule organizing center | focal adhesion | cell | lamellipodium | cytoplasm | cell-substrate junction | intracellular organelle | actin cytoskeleton | dendritic tree | apical part of cell | cell projection | neuron spine | postsynapse | plasma membrane | actomyosin | cell leading edge | perinuclear region of cytoplasm | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | cell periphery | cell-substrate adherens junction | stress fiber | cytosol | cytoskeleton | intracellular | cell junction | actin filament bundle | membrane
