QuickView for PTPN1;jsessionid=18A75D9863E3D88E6DDBC8BED547E8D2;jsessionid=0F07C59F20A16930410EC688F31E582F;jsessionid=26910138D84E68DA780094207382E8E9 (gene)
- Gene Symbol:
- PTPN1
Bos taurus - Full name:
- protein tyrosine phosphatase, non-receptor type 1
- Synonyms:
- N/A
- Genomic Location:
- Chr 13: 79549390-79610066
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
RSRFC4_01 , OCT1_06 , MEF2_03 , RSRFC4_Q2 , ZIC1_01 , ZIC2_01 , GGGNRMNNYCAT_UNKNOWN , GGCAGCT_MIR22 , TGCCTTA_MIR124A , ACCATTT_MIR522
GO Molecular Function
ephrin receptor binding | kinase binding | cation binding | protein kinase binding | receptor tyrosine kinase binding | enzyme binding | phosphatase activity | signaling receptor binding | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | ion binding | protein tyrosine kinase binding | protein binding | zinc ion binding | phosphoric ester hydrolase activity | transition metal ion binding | metal ion binding
GO Biological Process
regulation of JUN kinase activity | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | regulation of intracellular protein transport | negative regulation of MAPK cascade | actin filament-based process | response to endoplasmic reticulum stress | protein dephosphorylation | regulation of endoplasmic reticulum unfolded protein response | regulation of cellular localization | intracellular signal transduction | regulation of localization | peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | actin cytoskeleton organization | response to hormone | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | cellular process | negative regulation of signaling | regulation of vascular endothelial growth factor receptor signaling pathway | positive regulation of protein kinase activity | endoplasmic reticulum unfolded protein response | negative regulation of response to endoplasmic reticulum stress | negative regulation of apoptotic process | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | response to peptide hormone | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of cellular protein metabolic process | cellular response to unfolded protein | cellular response to organonitrogen compound | response to topologically incorrect protein | cellular component organization | MAPK cascade | cellular response to topologically incorrect protein | phosphatase activity | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | negative regulation of vascular endothelial growth factor receptor signaling pathway | regulation of cellular protein localization | JNK cascade | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | negative regulation of protein kinase activity | regulation of response to endoplasmic reticulum stress | response to peptide | positive regulation of receptor catabolic process | platelet-derived growth factor receptor-beta signaling pathway | negative regulation of endoplasmic reticulum unfolded protein response | regulation of protein transport | negative regulation of metabolic process | positive regulation of protein serine/threonine kinase activity | protein modification process | regulation of peptide transport | regulation of PERK-mediated unfolded protein response | macromolecule modification | negative regulation of ERK1 and ERK2 cascade | protein tyrosine phosphatase activity | activation of protein kinase activity | regulation of intracellular transport | stress-activated protein kinase signaling cascade | regulation of cellular response to stress | response to nitrogen compound | cellular response to hormone stimulus | regulation of protein tyrosine kinase activity | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | cellular response to peptide hormone stimulus | regulation of MAPK cascade | phosphorus metabolic process | cellular response to insulin stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | platelet-derived growth factor receptor signaling pathway | cellular response to stress | cellular response to peptide | insulin receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of hepatocyte growth factor receptor signaling pathway | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | phosphoprotein phosphatase activity | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of JNK cascade | negative regulation of cellular response to growth factor stimulus | positive regulation of intracellular signal transduction | negative regulation of protein serine/threonine kinase activity | negative regulation of PERK-mediated unfolded protein response | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | regulation of apoptotic signaling pathway | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | negative regulation of MAP kinase activity | regulation of cellular response to growth factor stimulus | positive regulation of molecular function | activation of MAPK activity | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | IRE1-mediated unfolded protein response | response to insulin | cell surface receptor signaling pathway | metabolic process | negative regulation of programmed cell death | actin cytoskeleton reorganization | regulation of vesicle-mediated transport | organic substance metabolic process | negative regulation of intrinsic apoptotic signaling pathway | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | regulation of phosphate metabolic process | cytoskeleton organization | regulation of JNK cascade | positive regulation of MAPK cascade | negative regulation of protein metabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | dephosphorylation | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of endocytosis | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | cellular protein metabolic process | response to unfolded protein | positive regulation of MAP kinase activity | organelle organization | cellular protein modification process | regulation of transport | peptidyl-tyrosine dephosphorylation | response to organonitrogen compound | positive regulation of JUN kinase activity | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | activation of JUN kinase activity | negative regulation of cell death | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | cytoplasmic side of membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | plasma membrane | cytoplasmic side of endoplasmic reticulum membrane | vesicle | endosome | membrane-bounded organelle | organelle | cell periphery | early endosome | intracellular vesicle | intracellular | sorting endosome | membrane
