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QuickView for PTPRJ;jsessionid=9923B6A7704CD982F8915805818E669C;jsessionid=5A715CF43553335F65AAE18CA46995D4;jsessionid=813C089E203A6D03710712B69D8BC8B9 (gene)


Gene Symbol:
Ptprj Rattus norvegicus Rattus norvegicus
Full name:
protein tyrosine phosphatase, receptor type, J
Synonyms:
DEP-1, receptor-type tyrosine-protein phosphatase eta, density enhanced phosphatase-1
Genomic Location:
Chr 3: 74796764-74935540
Description:
protein tyrosine phosphatase expressed in smooth muscle cells; may be involved in cell adhesion or cell-cell signaling
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_017269
Protein Names
No proteins found.



GO Molecular Function

beta-catenin binding | kinase binding | protein kinase binding | platelet-derived growth factor receptor binding | enzyme binding | mitogen-activated protein kinase binding | phosphatase activity | signaling receptor binding | hydrolase activity | protein tyrosine phosphatase activity | catalytic activity | gamma-catenin binding | phosphoprotein phosphatase activity | hydrolase activity, acting on ester bonds | identical protein binding | protein binding | phosphoric ester hydrolase activity | delta-catenin binding | growth factor receptor binding

GO Biological Process

negative regulation of signaling receptor activity | regulation of leukocyte chemotaxis | negative regulation of phosphorylation | positive regulation of locomotion | negative regulation of MAPK cascade | negative regulation of immune system process | protein dephosphorylation | positive regulation of cellular component organization | positive regulation of adherens junction organization | regulation of localization | regulation of immune system process | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | cell differentiation | nervous system development | negative regulation of protein phosphorylation | neurogenesis | positive regulation of cell adhesion | positive regulation of cellular component movement | blood vessel morphogenesis | cellular process | positive regulation of macrophage migration | regulation of cell motility | negative regulation of signaling | positive regulation of blood coagulation | negative regulation of T cell receptor signaling pathway | hemostasis | regulation of chemotaxis | negative regulation of cell migration | negative regulation of cellular metabolic process | regulation of T cell receptor signaling pathway | regulation of platelet activation | negative regulation of cell motility | regulation of protein kinase B signaling | regulation of immune response | regulation of cellular process | regulation of metabolic process | gliogenesis | negative regulation of epidermal growth factor receptor signaling pathway | phosphatase activity | response to stimulus | vasculature development | positive regulation of immune system process | response to stress | negative regulation of protein kinase activity | regulation of cell proliferation | tube morphogenesis | positive regulation of cell activation | cardiovascular system development | blood circulation | negative regulation of metabolic process | regulation of wound healing | protein modification process | regulation of cell adhesion | macromolecule modification | protein tyrosine phosphatase activity | positive regulation of cell-matrix adhesion | positive chemotaxis | blood vessel development | blood coagulation | locomotion | positive regulation of cell junction assembly | system development | positive regulation of response to wounding | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | negative regulation of phosphate metabolic process | regulation of adherens junction organization | multicellular organism development | negative regulation of catalytic activity | regulation of MAPK cascade | phosphorus metabolic process | positive regulation of protein kinase B signaling | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of granulocyte chemotaxis | regulation of phosphorylation | wound healing | positive regulation of chemotaxis | platelet-derived growth factor receptor signaling pathway | phosphoprotein phosphatase activity | regulation of blood coagulation | regulation of platelet-derived growth factor receptor signaling pathway | regulation of nitrogen compound metabolic process | regulation of cell migration | regulation of cell-substrate adhesion | enzyme linked receptor protein signaling pathway | regulation of vascular permeability | positive regulation of intracellular signal transduction | negative regulation of protein serine/threonine kinase activity | regulation of cellular component movement | positive regulation of cell migration | negative regulation of protein kinase B signaling | regulation of cellular protein metabolic process | glial cell differentiation | positive regulation of macrophage chemotaxis | regulation of leukocyte migration | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of platelet activation | positive regulation of leukocyte chemotaxis | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | heart development | regulation of protein phosphorylation | regulation of locomotion | negative regulation of MAP kinase activity | negative regulation of cell growth | coagulation | regulation of signaling receptor activity | protein metabolic process | positive regulation of focal adhesion assembly | regulation of growth | regulation of kinase activity | response to wounding | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | regulation of focal adhesion assembly | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of body fluid levels | positive regulation of coagulation | oligodendrocyte differentiation | negative regulation of ERBB signaling pathway | positive regulation of cellular component biogenesis | organic substance metabolic process | regulation of epidermal growth factor receptor signaling pathway | animal organ development | positive regulation of cell-substrate adhesion | negative regulation of cellular protein metabolic process | regulation of cell activation | negative regulation of cellular component movement | positive regulation of leukocyte migration | regulation of phosphate metabolic process | positive regulation of wound healing | negative regulation of vascular permeability | negative regulation of protein metabolic process | regulation of response to wounding | regulation of cell communication | dephosphorylation | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of ERBB signaling pathway | cellular protein metabolic process | anatomical structure morphogenesis | developmental process | regulation of cell growth | cellular protein modification process | tube development | regulation of cell junction assembly | negative regulation of cell proliferation | peptidyl-tyrosine dephosphorylation | regulation of macrophage chemotaxis | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | cellular metabolic process | negative regulation of platelet-derived growth factor receptor signaling pathway | positive regulation of cell motility | circulatory system development | chemotaxis | negative regulation of locomotion | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | regulation of cell-matrix adhesion | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | immunological synapse | ruffle | cell projection membrane | cell | intrinsic component of membrane | ruffle membrane | leading edge membrane | cell-cell junction | cell projection | plasma membrane | cell leading edge | cell periphery | cell surface | cell junction | membrane