QuickView for Proc;jsessionid=6AC349B461F19B519A12DF3AD4E588CB;jsessionid=5945576B27A95A7D3E98FCAE55A4A86E (gene)
- Gene Symbol:
- Proc
Rattus norvegicus - Full name:
- protein C, inactivator of coagulation factors Va and VIIIa
- Synonyms:
- vitamin K-dependent protein C, anticoagulant protein C, autoprothrombin IIA, blood coagulation factor XIV, protein C
- Genomic Location:
- Chr 18: 24563368-24573715
- Description:
-
vitamin K-dependent zymogen that acts as a serine protease upon activation; catalyzes the inactivation of blood coagulation cofactors Va and VIIIa
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
protein self-association | cation binding | hydrolase activity | catalytic activity | serine hydrolase activity | ion binding | oligopeptidase activity | protein binding | serine-type endopeptidase activity | serine-type peptidase activity | calcium ion binding | endopeptidase activity | metal ion binding | peptidase activity
GO Biological Process
proteolysis | regulation of cell development | regulation of programmed cell death | negative regulation of cellular process | positive regulation of developmental process | negative regulation of inflammatory response | hemostasis | negative regulation of apoptotic process | regulation of cell differentiation | positive regulation of endothelial cell differentiation | negative regulation of wound healing | regulation of cellular process | regulation of apoptotic process | hepaticobiliary system development | response to stimulus | response to stress | regulation of epithelial cell differentiation | regulation of wound healing | blood coagulation | system development | nitrogen compound metabolic process | multicellular organism development | wound healing | liver development | regulation of blood coagulation | positive regulation of cell differentiation | negative regulation of response to wounding | regulation of establishment of endothelial barrier | positive regulation of establishment of endothelial barrier | coagulation | oligopeptidase activity | protein metabolic process | gland development | response to wounding | anatomical structure development | metabolic process | positive regulation of cell development | regulation of body fluid levels | negative regulation of programmed cell death | organic substance metabolic process | animal organ development | serine-type endopeptidase activity | serine-type peptidase activity | regulation of response to wounding | endopeptidase activity | regulation of developmental process | developmental process | negative regulation of coagulation | positive regulation of epithelial cell differentiation | regulation of endothelial cell differentiation | regulation of circulating fibrinogen levels | negative regulation of blood coagulation | peptidase activity | regulation of cell death | negative regulation of cell death | regulation of inflammatory response | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | Golgi apparatus | endomembrane system | extracellular region | membrane-bounded organelle | organelle | extracellular space | intracellular
