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QuickView for RAPGEF4;jsessionid=D6DF79AF810FF90789B4CCA28C77F57E;jsessionid=4632FE608AB397A69FEFEB512701098A;jsessionid=62E01DBF1D22BFE64AFD5E52E538FC0E (gene)

Summary
General Info

Gene Symbol:: epac-1 C. elegans
Full name:: Exchange Protein Activated by Cyclic AMP
Synonyms:: epac-1, T20G5.5
Genomic Location:: Chr III: 10187597-10195237

Orthologs:: Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
External Links:: Entrez Gene

Transcription Factor Binding Sites:: AAAYRNCTG_UNKNOWN , AACTTT_UNKNOWN , HNF4ALPHA_Q6 , AP3_Q6 , E12_Q6 , E2A_Q2 , VDR_Q6 , GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D , TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P , TTGCACT_MIR130A_MIR301_MIR130B , TGCACTT_MIR519C_MIR519B_MIR519A , TTTGCAC_MIR19A_MIR19B , CATTTCA_MIR203 , GGGCATT_MIR365 , GTGCCAA_MIR96 , CAGGTG_E12_Q6 , TGCCAAR_NF1_Q6 , GGGCGGR_SP1_Q6 , TATAAA_TATA_01 , GCCATNTTG_YY1_Q6

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TRANSCRIPTS & PROTEINS
ASSOCIATED SNPs

Transcripts Names
NM_066855

Protein Names
P34578

GO Molecular Function

guanyl-nucleotide exchange factor activity | GTPase binding | enzyme binding | molecular function regulator | protein binding

GO Biological Process

guanyl-nucleotide exchange factor activity | intracellular signal transduction | cellular process | regulation of cellular process | small GTPase mediated signal transduction | response to stimulus | molecular function regulator | cell communication | signaling | signal transduction

GO Cellular Component

cell | intracellular

PATHWAYS

REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | REACTOME_REGULATION_OF_INSULIN_SECRETION | REACTOME_RAP1_SIGNALLING | REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | REACTOME_HEMOSTASIS | REACTOME_IMMUNE_SYSTEM | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION

PROTEIN FAMILY

DEP domain | Cyclic nucleotide-binding domain | Ras-like guanine nucleotide exchange factor, N-terminal | Ras guanine-nucleotide exchange factors catalytic domain | RmlC-like jelly roll fold | Cyclic nucleotide-binding-like | Ras guanine-nucleotide exchange factor, conserved site | Ras guanine nucleotide exchange factor domain superfamily | Ubiquitin-like domain superfamily | Winged helix-like DNA-binding domain superfamily | Winged helix DNA-binding domain superfamily | Ras guanine-nucleotide exchange factor catalytic domain superfamily