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QuickView for RIPK1;jsessionid=6D3E08C58BAFEDA659A1F338CEF9EC38;jsessionid=03680F558C8EDB45C36D5FFC84FEBC07;jsessionid=CA29C2F40D1AF48E4E14F833BC030E99 (gene)


Gene Symbol:
RIPK1 Gallus gallus Gallus gallus
Full name:
receptor (TNFRSF)-interacting serine-threonine kinase 1
Synonyms:
RIP-1
Genomic Location:
Chr 2: 67527226-67547169
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene


Transcripts Names
NM_204402
Protein Names
Q7ZZX8



GO Molecular Function

enzyme binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | protein domain specific binding | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | MAP kinase kinase kinase activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | JUN kinase kinase kinase activity | purine ribonucleoside triphosphate binding | protein binding | death domain binding | ubiquitin protein ligase binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of JUN kinase activity | protein homooligomerization | regulation of hydrogen peroxide-induced cell death | regulation of extrinsic apoptotic signaling pathway in absence of ligand | positive regulation of macromolecule biosynthetic process | response to cytokine | regulation of cellular response to oxidative stress | regulation of response to oxidative stress | intracellular signal transduction | positive regulation of apoptotic process | regulation of localization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | peptidyl-amino acid modification | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | regulation of MAP kinase activity | cellular response to tumor necrosis factor | positive regulation of phosphate metabolic process | regulation of necroptotic process | positive regulation of cellular biosynthetic process | cellular process | regulation of necrotic cell death | organic substance catabolic process | extrinsic apoptotic signaling pathway | negative regulation of signaling | positive regulation of protein kinase activity | negative regulation of apoptotic process | positive regulation of necrotic cell death | response to growth factor | positive regulation of catalytic activity | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | negative regulation of apoptotic signaling pathway | positive regulation of interleukin-8 production | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | catabolic process | positive regulation of cellular protein metabolic process | cellular component organization | MAPK cascade | positive regulation of tumor necrosis factor production | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | JNK cascade | positive regulation of immune system process | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | regulation of response to drug | protein serine/threonine kinase activity | programmed cell death | supramolecular fiber organization | cellular protein catabolic process | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | positive regulation of response to oxidative stress | macromolecule modification | activation of protein kinase activity | stress-activated protein kinase signaling cascade | positive regulation of macrophage differentiation | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of necroptotic process | regulation of MAPK cascade | phosphorus metabolic process | protein complex oligomerization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | amyloid fibril formation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | protein catabolic process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | positive regulation of cellular response to oxidative stress | MAP kinase kinase kinase activity | protein autophosphorylation | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | negative regulation of extrinsic apoptotic signaling pathway | T cell apoptotic process | cellular response to cytokine stimulus | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | regulation of apoptotic signaling pathway | protein phosphorylation | regulation of tumor necrosis factor production | phosphate-containing compound metabolic process | regulation of cellular response to drug | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | JUN kinase kinase kinase activity | positive regulation of response to drug | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | activation of MAPKK activity | activation of JNKK activity | regulation of protein metabolic process | positive regulation of signal transduction | regulation of protein phosphorylation | positive regulation of oxidative stress-induced cell death | regulation of RNA metabolic process | positive regulation of hydrogen peroxide-induced cell death | apoptotic signaling pathway | positive regulation of molecular function | activation of MAPK activity | protein-containing complex assembly | protein metabolic process | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | regulation of kinase activity | regulation of response to reactive oxygen species | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | cellular macromolecule catabolic process | peptidyl-serine autophosphorylation | cell surface receptor signaling pathway | metabolic process | negative regulation of I-kappaB kinase/NF-kappaB signaling | regulation of RNA biosynthetic process | negative regulation of programmed cell death | positive regulation of cell death | protein kinase activity | organic substance metabolic process | cell death | positive regulation of NF-kappaB transcription factor activity | positive regulation of programmed cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of ion transmembrane transport | positive regulation of cytokine production | regulation of JNK cascade | positive regulation of MAPK cascade | positive regulation of cellular response to drug | organonitrogen compound catabolic process | regulation of stress-activated MAPK cascade | regulation of cell communication | regulation of macrophage differentiation | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of transcription, DNA-templated | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | protein heterooligomerization | regulation of ATP:ADP antiporter activity | positive regulation of MAP kinase activity | regulation of developmental process | regulation of ion transport | kinase activity | peptidyl-serine phosphorylation | cellular protein modification process | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | regulation of anion transport | positive regulation of JUN kinase activity | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | regulation of cell death | activation of JUN kinase activity | negative regulation of cell death | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | plasma membrane protein complex | cytoplasm | death-inducing signaling complex | intracellular organelle | receptor complex | protein-containing complex | plasma membrane | mitochondrion | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane