QuickView for RNAPII;jsessionid=7BB27B6BEC1BCD5A324820F3706F9E7E;jsessionid=D44E70B0AF258DEA8330290BA5CD8AFB (gene)
- Gene Symbol:
- Polr2a
Mus musculus - Full name:
- polymerase (RNA) II (DNA directed) polypeptide A
- Synonyms:
- 220kDa, Rpb1, Rpo2-1, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase III largest subunit, RNA polymerase II 1, RNA polymerase II subunit B1
- Genomic Location:
- Chr 11: 69547912-69571725
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Bos taurus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
transcription regulatory region DNA binding | core promoter binding | cation binding | enzyme binding | nucleic acid binding | 5'-3' RNA polymerase activity | nucleotidyltransferase activity | catalytic activity | chromatin binding | ubiquitin-like protein ligase binding | DNA binding | promoter-specific chromatin binding | ion binding | organic cyclic compound binding | RNA polymerase II activity | protein binding | ubiquitin protein ligase binding | transferase activity, transferring phosphorus-containing groups | transferase activity | DNA-directed 5'-3' RNA polymerase activity | metal ion binding | heterocyclic compound binding | protein C-terminus binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | cellular process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | positive regulation of RNA splicing | cellular nitrogen compound metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | RNA polymerase II activity | regulation of RNA metabolic process | DNA-templated transcription, termination | metabolic process | regulation of RNA splicing | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | transcription, DNA-templated | cellular macromolecule biosynthetic process | heterocycle metabolic process | DNA-directed 5'-3' RNA polymerase activity | positive regulation of metabolic process | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
nuclear euchromatin | chromosome | intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | nucleolus | Prp19 complex | cytoplasm | intracellular organelle | euchromatin | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | transferase complex | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | RNA polymerase complex | membrane-enclosed lumen | nuclear chromatin | RNA polymerase II, core complex | intracellular | RNA polymerase II, holoenzyme
