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QuickView for RTN4;jsessionid=CEEF0A028C9D537A47EF2A4EB245F2F2;jsessionid=50750D8AEAAE04EC96832DA2346F931C;jsessionid=3DDADADA60F753A26886DF52D7FB04B7 (gene)


Gene Symbol:
Rtn4 Rattus norvegicus Rattus norvegicus
Full name:
reticulon 4
Synonyms:
NI-250, Nogo, Nogo-A, Vp20, r, rat N, rat NogoA, reticulon-4, GLUT4 vesicle 20kDa protein, NI-220/250, foocen, glut4 vesicle 20 kDa protein, neurite outgrowth inhibitor, nogo protein
Genomic Location:
Chr 14: 110725089-110772582
Description:
a myelin protein that is a potent inhibitor of neurite growth
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

enzyme binding | protein-containing complex binding | ubiquitin-like protein ligase binding | protein binding | ubiquitin protein ligase binding

GO Biological Process

endoplasmic reticulum tubular network membrane organization | brain development | nucleus organization | positive regulation of locomotion | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cellular localization | positive regulation of axon regeneration | regulation of cell development | protein stabilization | regulation of localization | negative regulation of cellular process | endoplasmic reticulum tubular network formation | positive regulation of developmental process | nuclear pore complex assembly | cell differentiation | positive regulation of epithelial cell proliferation | nervous system development | epithelial to mesenchymal transition | positive regulation of axonogenesis | neurogenesis | positive regulation of cellular component movement | positive regulation of collateral sprouting | generation of neurons | membrane organization | mesenchyme development | blood vessel morphogenesis | cellular process | negative regulation of axonogenesis | regulation of catecholamine secretion | regulation of cell motility | localization | heart morphogenesis | forebrain cell migration | negative regulation of axon regeneration | neuron development | negative regulation of developmental growth | endomembrane system organization | regulation of neuron projection development | tissue development | regulation of neurological system process | regulation of cell differentiation | cell recognition | regulation of protein kinase B signaling | regulation of cellular process | positive regulation of cell growth | gliogenesis | cellular component organization | negative regulation of dendrite extension | negative regulation of cell morphogenesis involved in differentiation | endoplasmic reticulum membrane organization | positive regulation of epithelial cell migration | head development | cranial nerve development | response to stimulus | vasculature development | regulation of cellular protein localization | cerebral cortex radial glia guided migration | positive regulation of cellular protein localization | regulation of response to drug | regulation of cell proliferation | negative regulation of neuron projection development | regulation of mammary gland epithelial cell proliferation | tube morphogenesis | telencephalon cell migration | regulation of dendrite extension | positive regulation of mammary gland epithelial cell proliferation | cardiovascular system development | regulation of neuron projection regeneration | positive regulation of gliogenesis | regulation of cellular component size | cellular component assembly | regulation of axon extension | regulation of morphogenesis of a branching structure | positive regulation of ERBB signaling pathway | blood vessel development | regulation of cellular response to stress | locomotion | system development | positive regulation of response to wounding | regulation of signal transduction | negative regulation of growth | regulation of protein stability | positive regulation of neuron projection development | multicellular organism development | response to activity | cell migration | positive regulation of protein localization to endoplasmic reticulum | regulation of axonogenesis | positive regulation of catecholamine secretion | positive regulation of protein kinase B signaling | positive regulation of neuron projection regeneration | regulation of sensory perception of pain | cardiac epithelial to mesenchymal transition | telencephalon development | negative regulation of formation of growth cone in injured axon | positive regulation of collateral sprouting of injured axon | regulation of neuron differentiation | axon development | positive regulation of secretion | neuron recognition | animal organ morphogenesis | regulation of cell migration | glial cell migration | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | regulation of cellular component movement | axonal fasciculation | positive regulation of cell differentiation | positive regulation of cell migration | glial cell differentiation | angiogenesis | cellular protein-containing complex assembly | cerebral cortex cell migration | pore complex assembly | negative regulation of response to wounding | positive regulation of response to drug | positive regulation of signal transduction | heart development | positive regulation of cell proliferation | regulation of locomotion | neuron projection fasciculation | positive regulation of transport | cerebral cortex development | negative regulation of cell growth | regulation of dopamine secretion | neuron differentiation | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | regulation of protein localization to endoplasmic reticulum | regulation of growth | negative regulation of cell projection organization | olfactory nerve development | regulation of intracellular signal transduction | nuclear pore organization | anatomical structure development | positive regulation of neurogenesis | cell projection organization | positive regulation of cell development | mesenchymal cell differentiation | oligodendrocyte differentiation | positive regulation of glial cell differentiation | negative regulation of axon extension | regulation of secretion | neuron projection development | animal organ development | positive regulation of ion transport | cerebral cortex radially oriented cell migration | forebrain development | negative regulation of neuron differentiation | nerve development | pallium development | regulation of axon regeneration | anatomical structure formation involved in morphogenesis | regulation of epithelial cell migration | regulation of glial cell differentiation | regulation of collateral sprouting | regulation of response to wounding | regulation of cell communication | regulation of gliogenesis | positive regulation of developmental growth | positive regulation of growth | cell development | regulation of ERBB signaling pathway | regulation of developmental growth | regulation of epithelial cell proliferation | positive regulation of dopamine secretion | regulation of cell size | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | regulation of ion transport | negative regulation of neuron projection regeneration | developmental process | organelle organization | regulation of cell growth | tube development | regulation of transport | central nervous system development | positive regulation of neuron differentiation | regulation of cell projection organization | endoplasmic reticulum tubular network organization | regulation of protein localization | positive regulation of cell motility | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell development | regulation of branching morphogenesis of a nerve | circulatory system development | aging | endoplasmic reticulum organization | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | negative regulation of neurogenesis | positive regulation of ERBB3 signaling pathway | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell body | cell | integral component of endoplasmic reticulum membrane | neuronal cell body | distal axon | dendrite terminus | intrinsic component of membrane | cytoplasm | intracellular organelle | intrinsic component of endoplasmic reticulum membrane | endoplasmic reticulum | dendritic tree | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | cell projection | endomembrane system | endoplasmic reticulum membrane | postsynapse | plasma membrane | nuclear envelope | postsynaptic density | asymmetric synapse | site of polarized growth | membrane-bounded organelle | nucleus | endoplasmic reticulum tubular network membrane | organelle | postsynaptic specialization | cell periphery | axon | growth cone | endoplasmic reticulum tubular network | dendritic growth cone | intracellular | myelin sheath | membrane