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QuickView for Raf1;jsessionid=A4FA50AFFC7B4E36528EC6D888A63367;jsessionid=F705A02BAD8F1D33EA21692AC9C341C3 (gene)


Gene Symbol:
Raf1 Mus musculus Mus musculus
Full name:
v-raf-leukemia viral oncogene 1
Synonyms:
6430402F14Rik, AA990557, BB129353, Craf1, D830050J10Rik, Raf-1, c-Raf, cRaf, v-Raf, RAF proto-oncogene serine/threonine-protein kinase, Craf1 transforming, murine sarcoma 3611 oncogene 1, proto-oncogene c-RAF, sarcoma 3611 oncogene, v-raf-1 leukemia viral oncogene 1
Genomic Location:
Chr 6: 115568591-115626653
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

kinase binding | enzyme activator activity | GTPase binding | cation binding | adenylate cyclase binding | protein kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | Ras GTPase binding | molecular function regulator | catalytic activity | ATP binding | adenylate cyclase activator activity | anion binding | adenyl nucleotide binding | MAP kinase kinase kinase activity | purine nucleotide binding | mitogen-activated protein kinase kinase binding | identical protein binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | small GTPase binding | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

positive regulation of macromolecule biosynthetic process | cellular response to glucose stimulus | insulin secretion involved in cellular response to glucose stimulus | intracellular signal transduction | enzyme activator activity | somatic stem cell population maintenance | regulation of programmed cell death | hormone secretion | establishment of localization | negative regulation of cellular process | regulation of MAP kinase activity | cell differentiation | cellular chemical homeostasis | glucose homeostasis | positive regulation of phosphate metabolic process | positive regulation of cellular biosynthetic process | cellular process | secretion | peptide hormone secretion | localization | cellular homeostasis | extrinsic apoptotic signaling pathway | protein transport | negative regulation of signaling | positive regulation of peptidyl-serine phosphorylation | immune system development | stem cell population maintenance | positive regulation of protein kinase activity | macromolecule localization | negative regulation of apoptotic process | response to hypoxia | response to growth factor | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | establishment of localization in cell | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | cellular component organization | MAPK cascade | head development | thyroid gland development | response to stimulus | thymus development | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | response to stress | regulation of cell proliferation | response to muscle stretch | response to glucose | protein serine/threonine kinase activity | programmed cell death | cellular localization | secretion by cell | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | macromolecule modification | cell-cell signaling | activation of protein kinase activity | insulin secretion | molecular function regulator | regulation of nucleic acid-templated transcription | apoptotic process | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | cellular glucose homeostasis | regulation of MAPK cascade | phosphorus metabolic process | adenylate cyclase activator activity | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of hormone levels | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | organic substance transport | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | MAP kinase kinase kinase activity | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | peptide transport | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | negative regulation of extrinsic apoptotic signaling pathway | regulation of cellular protein metabolic process | neurotrophin signaling pathway | phosphorylation | regulation of apoptotic signaling pathway | endocrine system development | protein phosphorylation | phosphate-containing compound metabolic process | peptide secretion | death-inducing signaling complex assembly | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | activation of MAPKK activity | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | response to monosaccharide | regulation of protein phosphorylation | regulation of RNA metabolic process | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | apoptotic signaling pathway | positive regulation of molecular function | activation of adenylate cyclase activity | protein-containing complex assembly | protein metabolic process | positive regulation of protein modification process | response to organic substance | gland development | neurotrophin TRK receptor signaling pathway | regulation of kinase activity | response to mechanical stimulus | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | amide transport | intermediate filament-based process | chemical homeostasis | hormone transport | protein kinase activity | negative regulation of protein complex assembly | organic substance metabolic process | maintenance of cell number | cell death | animal organ development | positive regulation of kinase activity | regulation of phosphate metabolic process | cytoskeleton organization | establishment of protein localization | positive regulation of MAPK cascade | regulation of peptidyl-serine phosphorylation | regulation of cell communication | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | regulation of transcription, DNA-templated | protein localization | positive regulation of phosphorylation | cellular protein metabolic process | enzyme regulator activity | positive regulation of MAP kinase activity | kinase activity | developmental process | organelle organization | cellular protein modification process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | intermediate filament cytoskeleton organization | positive regulation of nucleic acid-templated transcription | signal release | positive regulation of transcription by RNA polymerase II | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of cell death | protein secretion | response to carbohydrate | negative regulation of cell death | carbohydrate homeostasis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | face development | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | Golgi apparatus | pseudopodium | cell projection | endomembrane system | nucleoplasm | plasma membrane | nuclear speck | mitochondrion | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane