QuickView for Rrp5;jsessionid=800F601FF936792B0CA73BC4A5D8405D (gene)

Gene Symbol:

PDCD11 Homo sapiens

Full name:

programmed cell death 11

Synonyms:

ALG-4, ALG4, NFBP, RRP5, protein RRP5 homolog, NF-kappa-B-binding protein, apoptosis-linked gene 4, programmed cell death protein 11

Genomic Location:

Chr 10: 105146402-105196009

Description:

PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).

PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation of 18S rRNA (Sweet et al., 2003 [PubMed 14624448]; Sweet et al., 2008 [PubMed 17654514]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CAGCAGG_MIR370

Cytogenetic Map:

10q24.33

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