QuickView for SCF;jsessionid=9574E8CA51F66DFBB5909E94F444F147;jsessionid=674A76569B3C49E056F350F417DD1ABA;jsessionid=B2264B0B024E2F3B11C6F965DEFB03E0;jsessionid=44ED9A4ACDC97C5FB2F4B5715FEEAF65 (gene)

Gene Symbol:

CALU Homo sapiens

Full name:

calumenin

Synonyms:

calumenin, IEF SSP 9302, crocalbin-like protein, multiple EF-hand protein

Genomic Location:

Chr 7: 128166672-128198764

Description:

The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript v...

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The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Orthologs:

Mus musculus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  GAGACTG_MIR452 ,  CAGTGTT_MIR141_MIR200A ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GTAAACC_MIR2995P ,  IRF1_Q6 ,  TGACCTY_ERR1_Q2 ,  CTTTGTA_MIR524 ,  STAT3_02 ,  GCTCTTG_MIR335 ,  ATACCTC_MIR202 ,  EGR_Q6 ,  GTCTTCC_MIR7 ,  GGGCGGR_SP1_Q6 ,  GACTGTT_MIR212_MIR132 ,  RNGTGGGC_UNKNOWN ,  GTGCCTT_MIR506 ,  CETS1P54_01 ,  SCGGAAGY_ELK1_02 ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  IK2_01 ,  WTTGKCTG_UNKNOWN ,  ELK1_02 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  ATGAAGG_MIR205 ,  CACTTTG_MIR520G_MIR520H

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-205 ,  Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-299 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-335 ,  Predicted Gene Targets for miR-7 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-490

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Cytogenetic Map:

7q32.1

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