QuickView for SEPT6;jsessionid=654DC0DDB8110BA4FCC9E86868AF9755;jsessionid=E38B48A2A3718D85CE7419224338DA48;jsessionid=A543747F5B61F3BA97E3A777B71F2AEA (gene)

Gene Symbol:

SEPT6 Homo sapiens

Full name:

septin 6

Synonyms:

SEP2, SEPT2, septin-6, septin 2

Genomic Location:

Chr X: 118633715-118711361

Description:

This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encod...

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This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTTGCAG_MIR518A2 ,  AACTGAC_MIR223 ,  CTTTGCA_MIR527 ,  CAGCACT_MIR5123P ,  GAGCTGG_MIR337 ,  ATGCTGC_MIR103_MIR107

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-217 ,  Predicted Gene Targets for miR-223

Cytogenetic Map:

Xq24

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