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QuickView for SERPINA5;jsessionid=3F7B39273E422D4BEFCBBA89DB277CE6;jsessionid=B1F15BBCA2B1D70E67DD24D2F5A4D2D9;jsessionid=15427477B25CD82F1F53D341E7E9A9DD (gene)


Gene Symbol:
Serpina5 Rattus norvegicus Rattus norvegicus
Full name:
serpin family A member 5
Synonyms:
Pci, plasma serine protease inhibitor, protein C inhibitor, serine (or cysteine) peptidase inhibitor, clade A, member 5, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5, serpin peptidase inhibitor, clade A, member 5
Genomic Location:
Chr 6: 128156901-128161334
Description:
inhibits activated serine protease protein C in the anticoagulant protein C pathway; may play a role in reproduction
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Canis lupus familiaris
External Links:
Entrez Gene


Protein Names
Q66HL5
F7EMJ6



GO Molecular Function

endopeptidase inhibitor activity | isoprenoid binding | retinoid binding | cation binding | carboxylic acid binding | enzyme binding | lipid binding | enzyme inhibitor activity | phospholipid binding | molecular function regulator | anion binding | phosphatidylcholine binding | ion binding | protein binding | acrosin binding | serine-type endopeptidase inhibitor activity | peptidase inhibitor activity | enzyme regulator activity | retinoic acid binding | protease binding | organic acid binding | small molecule binding

GO Biological Process

endopeptidase inhibitor activity | developmental process involved in reproduction | negative regulation of cellular process | male gamete generation | negative regulation of proteolysis | reproductive system development | multicellular organismal reproductive process | regulation of proteolysis | negative regulation of cellular metabolic process | gamete generation | regulation of cellular process | regulation of metabolic process | enzyme inhibitor activity | reproduction | negative regulation of metabolic process | molecular function regulator | system development | reproductive process | multicellular organism development | negative regulation of catalytic activity | regulation of peptidase activity | regulation of catalytic activity | negative regulation of peptidase activity | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | seminal vesicle development | regulation of cellular metabolic process | regulation of protein metabolic process | multicellular organism reproduction | gland development | anatomical structure development | animal organ development | negative regulation of cellular protein metabolic process | serine-type endopeptidase inhibitor activity | negative regulation of protein metabolic process | negative regulation of molecular function | peptidase inhibitor activity | enzyme regulator activity | regulation of endopeptidase activity | reproductive structure development | developmental process | spermatogenesis | negative regulation of hydrolase activity | sexual reproduction | negative regulation of endopeptidase activity | multicellular organismal process

GO Cellular Component

secretory granule | intracellular membrane-bounded organelle | protein C inhibitor-coagulation factor XI complex | organelle membrane | protein C inhibitor-KLK3 complex | cytoplasmic vesicle | protein C inhibitor-TMPRSS7 complex | cell | protein C inhibitor-plasma kallikrein complex | protein C inhibitor-TMPRSS11E complex | external side of plasma membrane | cytoplasm | protease inhibitor complex | acrosomal vesicle | intracellular organelle | platelet alpha granule | secretory granule membrane | protein C inhibitor-thrombin complex | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | serine protease inhibitor complex | vesicle | extracellular exosome | protein C inhibitor-coagulation factor V complex | acrosomal membrane | extracellular region | platelet dense tubular network | membrane-bounded organelle | extracellular vesicle | organelle | protein C inhibitor-coagulation factor Xa complex | vesicle membrane | protein C inhibitor-PLAU complex | extracellular space | cell periphery | protein C inhibitor-PLAT complex | intracellular vesicle | cell surface | intracellular | membrane | cytoplasmic vesicle membrane