QuickView for SFTPA1;jsessionid=7F90671BF94EDD7742B2F6295F244611;jsessionid=A113203F26A6B990EF595C1802195E56;jsessionid=B350E2F1D29D93306C7765F4B8353E47 (gene)
- Gene Symbol:
- Sftpa1
Rattus norvegicus - Full name:
- surfactant protein A1
- Synonyms:
- PSAP, PSP-A, SP-A, Sftp1, Sftpa, Sftpl, pulmonary surfactant-associated protein A, Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A), pulmonary surfactant-associated protein A-like, surfactant, pulmonary-associated protein A1
- Genomic Location:
- Chr 16: 17570887-17574389
- Description:
-
binds LPS and modifies LPS-induced immune cell activation in the lung
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
cation binding | lipid binding | carbohydrate derivative binding | monosaccharide binding | ion binding | carbohydrate binding | lipopolysaccharide binding | metal ion binding | small molecule binding
GO Biological Process
response to extracellular stimulus | respiratory gaseous exchange | response to nutrient levels | response to cytokine | positive regulation of cellular component organization | response to lipopolysaccharide | regulation of localization | establishment of localization | response to hormone | opsonization | response to drug | tissue homeostasis | cellular process | localization | cellular response to nitric oxide | response to hypoxia | response to growth factor | response to inorganic substance | anatomical structure homeostasis | regulation of cellular process | response to stimulus | cellular response to mechanical stimulus | response to stress | multicellular organismal homeostasis | circadian rhythm | cellular response to inorganic substance | rhythmic process | response to molecule of bacterial origin | regulation of phagocytosis | response to nitrogen compound | chemical homeostasis within a tissue | response to external biotic stimulus | response to oxygen levels | cellular response to oxidative stress | cellular response to stress | response to lipid | response to corticosteroid | vesicle-mediated transport | response to nutrient | response to oxidative stress | surfactant homeostasis | response to hyperoxia | response to vitamin A | cellular response to drug | response to bacterium | homeostatic process | positive regulation of transport | response to retinoic acid | response to organic substance | cellular response to reactive nitrogen species | response to mechanical stimulus | import into cell | regulation of vesicle-mediated transport | chemical homeostasis | endocytosis | cellular response to reactive oxygen species | response to vitamin | response to reactive oxygen species | positive regulation of phagocytosis | response to epidermal growth factor | response to organic cyclic compound | regulation of endocytosis | response to biotic stimulus | regulation of transport | immune system process | response to nitric oxide | response to steroid hormone | response to interleukin-6 | phagocytosis | positive regulation of endocytosis | regulation of cellular component organization | response to other organism | response to glucocorticoid | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | late endosome | cytoplasmic vesicle | cell | multivesicular body | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | vesicle | collagen trimer | endosome | extracellular region | membrane-bounded organelle | organelle | extracellular space | rough endoplasmic reticulum | intracellular vesicle | intracellular
