QuickView for SGK-1;jsessionid=F53A3B3E54E9317A220D539A68200A67;jsessionid=C51F03F16087CC3416C3F31E1EAE1DAF (gene)
- Gene Symbol:
- Sgk1
Rattus norvegicus - Full name:
- serum/glucocorticoid regulated kinase 1
- Synonyms:
- Sgk, serine/threonine-protein kinase Sgk1, serine/threonine protein kinase SGK
- Genomic Location:
- Chr 1: 23501262-23506702
- Description:
-
may play a role in menory consolidation and spatial learning; may mediate aldosterone-induced signaling
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-133 , Predicted Gene Targets for miR-142-3p , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-19 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-299 , Predicted Gene Targets for miR-323 , Predicted Gene Targets for miR-365 , Predicted Gene Targets for miR-382
GO Molecular Function
kinase binding | cofactor binding | channel regulator activity | protein kinase binding | enzyme binding | ribonucleotide binding | lipid binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | phospholipid binding | molecular function regulator | catalytic activity | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | tau protein binding | purine nucleotide binding | 3-phosphoinositide-dependent protein kinase binding | potassium channel regulator activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | phosphatidylinositol binding | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | protein serine/threonine/tyrosine kinase activity | drug binding | kinase activity | heterocyclic compound binding | small molecule binding
GO Biological Process
regulation of supramolecular fiber organization | response to radiation | cell morphogenesis | regulation of microtubule polymerization or depolymerization | long-term memory | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | neuron projection morphogenesis | intracellular signal transduction | regulation of cell development | regulation of localization | regulation of programmed cell death | regulation of sodium ion transport | peptidyl-amino acid modification | response to hormone | negative regulation of cellular process | glucocorticoid mediated signaling pathway | positive regulation of developmental process | microtubule cytoskeleton organization | cell differentiation | nervous system development | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | regulation of organelle organization | generation of neurons | hormone-mediated signaling pathway | microtubule-based process | cellular process | channel regulator activity | cellular homeostasis | cell projection morphogenesis | visual learning | neuron development | negative regulation of microtubule polymerization or depolymerization | cellular sodium ion homeostasis | learning | negative regulation of apoptotic process | regulation of cell cycle | regulation of neuron projection development | response to peptide hormone | regulation of cell differentiation | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | cellular response to lipid | regulation of protein complex assembly | cellular response to organonitrogen compound | cellular component organization | positive regulation of dendrite morphogenesis | associative learning | response to stimulus | response to stress | response to peptide | protein serine/threonine kinase activity | programmed cell death | supramolecular fiber organization | cellular response to organic cyclic compound | protein modification process | steroid hormone mediated signaling pathway | macromolecule modification | molecular function regulator | metal ion homeostasis | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | response to light stimulus | system development | sodium ion homeostasis | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | cellular response to peptide hormone stimulus | phosphorus metabolic process | learning or memory | cellular response to DNA damage stimulus | cellular response to insulin stimulus | regulation of neuron differentiation | cellular response to stress | response to lipid | nervous system process | cellular response to peptide | cellular ion homeostasis | positive regulation of cell projection organization | response to corticosteroid | positive regulation of cell differentiation | cognition | cellular response to glucocorticoid stimulus | microtubule depolymerization | phosphorylation | potassium channel regulator activity | protein phosphorylation | cation homeostasis | cellular response to corticosteroid stimulus | phosphate-containing compound metabolic process | cellular cation homeostasis | negative regulation of microtubule polymerization | cell communication | homeostatic process | cellular protein complex disassembly | positive regulation of transport | positive regulation of dendrite development | regulation of microtubule-based process | neuron differentiation | regulation of cell morphogenesis involved in differentiation | protein metabolic process | negative regulation of protein polymerization | regulation of growth | response to organic substance | visual behavior | response to insulin | anatomical structure development | regulation of dendrite morphogenesis | positive regulation of neurogenesis | cell projection organization | metabolic process | positive regulation of cell development | regulation of microtubule polymerization | negative regulation of programmed cell death | negative regulation of cytoskeleton organization | chemical homeostasis | behavior | protein kinase activity | neuron projection development | negative regulation of protein complex assembly | organic substance metabolic process | cell death | positive regulation of ion transport | positive regulation of sodium ion transport | ion homeostasis | cytoskeleton organization | protein depolymerization | cellular response to steroid hormone stimulus | microtubule polymerization or depolymerization | memory | regulation of dendrite development | signaling | positive regulation of growth | response to organic cyclic compound | cellular monovalent inorganic cation homeostasis | cell development | protein-containing complex disassembly | cellular protein metabolic process | anatomical structure morphogenesis | protein serine/threonine/tyrosine kinase activity | regulation of nervous system development | regulation of developmental process | regulation of ion transport | kinase activity | developmental process | organelle organization | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | regulation of transport | response to organonitrogen compound | cellular metal ion homeostasis | negative regulation of supramolecular fiber organization | positive regulation of neuron differentiation | regulation of cell projection organization | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | response to steroid hormone | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of cytoskeleton organization | signal transduction | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | neuron projection | cell | nuclear lumen | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear body | nuclear outer membrane-endoplasmic reticulum membrane network | cell projection | endomembrane system | endoplasmic reticulum membrane | nucleoplasm | plasma membrane | nuclear speck | perinuclear region of cytoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | cytosol | intracellular | membrane
