QuickView for SIAH1;jsessionid=CEB40C348C45423EDC9FD97E0F4A3375;jsessionid=ACA811BA5068D5C56925D8F3B229B83C (gene)
- Gene Symbol:
- Siah1a
Mus musculus - Full name:
- siah E3 ubiquitin protein ligase 1A
- Synonyms:
- AA982064, AI853500, Sinh1a, E3 ubiquitin-protein ligase SIAH1A, RING-type E3 ubiquitin transferase SIAH1A, mSiah-1a, seven in absentia 1A, seven in absentia homolog 1a, siah-1a
- Genomic Location:
- Chr 8: 89247906-89269833
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-129 , Predicted Gene Targets for miR-135 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-193 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-200b , Predicted Gene Targets for miR-205 , Predicted Gene Targets for miR-299 , Predicted Gene Targets for miR-30-3p , Predicted Gene Targets for miR-329
GO Molecular Function
cation binding | enzyme binding | disordered domain specific binding | catalytic activity | protein domain specific binding | ubiquitin-like protein transferase activity | ubiquitin conjugating enzyme binding | identical protein binding | ubiquitin protein ligase activity | ion binding | protein binding | protein homodimerization activity | zinc ion binding | protein dimerization activity | ubiquitin-protein transferase activity | ubiquitin-like protein conjugating enzyme binding | transferase activity | transition metal ion binding | ubiquitin-like protein ligase activity | metal ion binding | protein C-terminus binding
GO Biological Process
positive regulation of apoptotic process | proteolysis | regulation of programmed cell death | neuron death | cell differentiation | male gamete generation | positive regulation of intrinsic apoptotic signaling pathway | male meiotic nuclear division | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | multicellular organismal reproductive process | regulation of multicellular organism growth | gamete generation | regulation of cellular process | regulation of apoptotic process | catabolic process | cellular component organization | male meiosis I | programmed cell death | protein destabilization | reproduction | cellular protein catabolic process | proteasomal protein catabolic process | protein modification process | macromolecule modification | apoptotic process | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | regulation of protein stability | multicellular organism development | regulation of intrinsic apoptotic signaling pathway | cell cycle | protein catabolic process | protein modification by small protein conjugation | neuron apoptotic process | positive regulation of intracellular signal transduction | ubiquitin protein ligase activity | regulation of apoptotic signaling pathway | post-embryonic development | positive regulation of signal transduction | proteasome-mediated ubiquitin-dependent protein catabolic process | multicellular organism reproduction | protein metabolic process | regulation of growth | protein ubiquitination | regulation of intracellular signal transduction | cellular macromolecule catabolic process | anatomical structure development | nuclear division | metabolic process | ubiquitin-protein transferase activity | positive regulation of cell death | organic substance metabolic process | cell death | positive regulation of programmed cell death | protein modification by small protein conjugation or removal | meiosis I | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | meiotic cell cycle | regulation of cell communication | regulation of developmental growth | cellular protein metabolic process | regulation of developmental process | developmental process | organelle organization | spermatogenesis | cellular protein modification process | cellular metabolic process | regulation of cell death | modification-dependent protein catabolic process | sexual reproduction | positive regulation of apoptotic signaling pathway | positive regulation of signaling | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cytoplasmic vesicle | cell | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | endomembrane system | plasma membrane | vesicle | transferase complex | beta-catenin destruction complex | endosome | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | cell periphery | SCF ubiquitin ligase complex | early endosome | cytosol | intracellular vesicle | intracellular | membrane
