QuickView for SKP2;jsessionid=B8637F159C0D0001C8AFD1303519C6FE;jsessionid=8829532602CC67A89C833A0F86C50C9B (gene)
- Gene Symbol:
- Skp2
Rattus norvegicus - Full name:
- S-phase kinase associated protein 2
- Synonyms:
- RGD1562456, S-phase kinase-associated protein 2, S-phase kinase-associated protein 2 (p45), S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
- Genomic Location:
- Chr 2: 58770295-58797349
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
catalytic activity | ubiquitin-like protein transferase activity | identical protein binding | ubiquitin protein ligase activity | protein binding | transferase activity, transferring phosphorus-containing groups | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity | kinase activity
GO Biological Process
positive regulation of smooth muscle cell proliferation | response to extracellular stimulus | proteolysis | regulation of programmed cell death | cellular response to extracellular stimulus | cellular process | organic substance catabolic process | proteolysis involved in cellular protein catabolic process | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of intracellular steroid hormone receptor signaling pathway | regulation of cell proliferation | positive regulation of protein polyubiquitination | regulation of protein ubiquitination | cellular protein catabolic process | proteasomal protein catabolic process | cell cycle G1/S phase transition | protein modification process | macromolecule modification | nitrogen compound metabolic process | regulation of signal transduction | phosphorus metabolic process | regulation of intracellular estrogen receptor signaling pathway | cell cycle | protein catabolic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | ubiquitin protein ligase activity | regulation of cellular protein metabolic process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | G2/M transition of mitotic cell cycle | phosphorylation | mitotic cell cycle phase transition | phosphate-containing compound metabolic process | positive regulation of intracellular estrogen receptor signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | cell cycle G2/M phase transition | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | positive regulation of protein modification process | protein ubiquitination | cellular macromolecule catabolic process | mitotic cell cycle | metabolic process | ubiquitin-protein transferase activity | organic substance metabolic process | protein modification by small protein conjugation or removal | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | positive regulation of intracellular steroid hormone receptor signaling pathway | cellular protein metabolic process | kinase activity | cellular protein modification process | cell cycle phase transition | cellular response to cell-matrix adhesion | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | regulation of smooth muscle cell proliferation | modification-dependent protein catabolic process | positive regulation of protein ubiquitination | positive regulation of signaling | regulation of signaling | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | transferase complex | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | SCF ubiquitin ligase complex | cytosol | intracellular
