QuickView for SOCS3;jsessionid=A5744C5969E7C042159E268B6CB64CB4;jsessionid=F0CC5C6DBCF2831EC73E006864F699F7;jsessionid=AECC324142AD33EF78EFCA17EE8A694F;jsessionid=6DBBDD0B7F41DBA8DB5AA8D90120BBDF (gene)
- Gene Symbol:
- Socs3
Mus musculus - Full name:
- suppressor of cytokine signaling 3
- Synonyms:
- Cis3, Cish3, EF-10, Ef10, SSI-3, Ssi3, suppressor of cytokine signaling 3, CIS-3, E2a-Pbx1 target gene in fibroblasts 10, STAT-induced STAT inhibitor 3, cytokine inducible SH2-containing protein 3
- Genomic Location:
- Chr 11: 117827393-117830476
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
protein phosphorylated amino acid binding | kinase regulator activity | phosphotyrosine residue binding | molecular function regulator | 1-phosphatidylinositol-3-kinase regulator activity | phosphatidylinositol 3-kinase regulator activity | phosphoprotein binding | protein binding | enzyme regulator activity
GO Biological Process
negative regulation of phosphorylation | negative regulation of cellular response to insulin stimulus | response to cytokine | developmental process involved in reproduction | intracellular signal transduction | morphogenesis of an epithelium | regulation of programmed cell death | phosphatidylinositol metabolic process | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | JAK-STAT cascade | negative regulation of protein phosphorylation | phospholipid metabolic process | cellular process | negative regulation of inflammatory response | negative regulation of signaling | kinase regulator activity | reproductive system development | negative regulation of apoptotic process | regulation of tyrosine phosphorylation of STAT protein | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of apoptotic process | labyrinthine layer morphogenesis | regulation of metabolic process | epithelium development | cellular lipid metabolic process | response to stimulus | vasculature development | regulation of peptidyl-tyrosine phosphorylation | negative regulation of JAK-STAT cascade | trophoblast giant cell differentiation | branching involved in labyrinthine layer morphogenesis | reproduction | negative regulation of tyrosine phosphorylation of STAT protein | cardiovascular system development | negative regulation of metabolic process | embryo development | regulation of phosphatidylinositol 3-kinase activity | molecular function regulator | embryonic placenta development | blood vessel development | system development | reproductive process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | phosphorus metabolic process | regulation of catalytic activity | lipid metabolic process | regulation of phosphorylation | 1-phosphatidylinositol-3-kinase regulator activity | phosphatidylinositol 3-kinase regulator activity | organophosphate metabolic process | regulation of nitrogen compound metabolic process | placenta blood vessel development | negative regulation of insulin receptor signaling pathway | positive regulation of cell differentiation | cellular response to cytokine stimulus | cell differentiation involved in embryonic placenta development | labyrinthine layer development | regulation of cellular protein metabolic process | phosphorylation | phosphate-containing compound metabolic process | lipid phosphorylation | regulation of lipid kinase activity | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | lipid modification | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | glycerolipid metabolic process | regulation of phospholipid metabolic process | embryonic morphogenesis | regulation of growth | response to organic substance | tissue morphogenesis | regulation of JAK-STAT cascade | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | metabolic process | negative regulation of programmed cell death | embryonic organ development | organic substance metabolic process | animal organ development | regulation of insulin receptor signaling pathway | negative regulation of cellular protein metabolic process | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | morphogenesis of a branching epithelium | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | cellular response to leukemia inhibitory factor | signaling | negative regulation of peptidyl-tyrosine phosphorylation | enzyme regulator activity | phosphatidylinositol phosphorylation | morphogenesis of a branching structure | anatomical structure morphogenesis | reproductive structure development | regulation of developmental process | glycerophospholipid metabolic process | developmental process | embryonic placenta morphogenesis | in utero embryonic development | regulation of lipid metabolic process | cellular metabolic process | placenta development | cellular response to organic substance | regulation of cell death | spongiotrophoblast layer development | spongiotrophoblast differentiation | negative regulation of cell death | circulatory system development | regulation of inflammatory response | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
catalytic complex | phosphatidylinositol 3-kinase complex | extrinsic component of membrane | cell | cytoplasm | protein-containing complex | transferase complex | intracellular | membrane
