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QuickView for SOCS3;jsessionid=A5744C5969E7C042159E268B6CB64CB4;jsessionid=F0CC5C6DBCF2831EC73E006864F699F7;jsessionid=AECC324142AD33EF78EFCA17EE8A694F;jsessionid=28404600B5079B12D7F1123C9E162A06 (gene)


Gene Symbol:
Socs3 Rattus norvegicus Rattus norvegicus
Full name:
suppressor of cytokine signaling 3
Synonyms:
Cish3, Socs-3, Ssi-3, suppressor of cytokine signaling 3, cytokine inducible SH2-containing protein 3, cytokine-inducible SH2 protein 3
Genomic Location:
Chr 10: 107958468-107959330
Description:
regulates cytokine levels to modulate inflammation
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Bos taurus Gallus gallus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_053565
XM_008768398
Protein Names
G3V6D2
Q9QYV5
O88583



GO Molecular Function

protein phosphorylated amino acid binding | phosphotyrosine residue binding | phosphoprotein binding | protein binding

GO Biological Process

response to extracellular stimulus | negative regulation of phosphorylation | response to radiation | negative regulation of cellular response to insulin stimulus | response to nutrient levels | response to cytokine | response to lipopolysaccharide | developmental process involved in reproduction | intracellular signal transduction | morphogenesis of an epithelium | regulation of programmed cell death | response to hormone | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | JAK-STAT cascade | response to drug | negative regulation of protein phosphorylation | cellular process | negative regulation of inflammatory response | negative regulation of signaling | reproductive system development | response to progesterone | response to estradiol | negative regulation of apoptotic process | response to hypoxia | regulation of tyrosine phosphorylation of STAT protein | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | regulation of cell differentiation | regeneration | regulation of cellular process | regulation of apoptotic process | labyrinthine layer morphogenesis | regulation of metabolic process | epithelium development | response to stimulus | vasculature development | regulation of peptidyl-tyrosine phosphorylation | negative regulation of JAK-STAT cascade | response to stress | trophoblast giant cell differentiation | branching involved in labyrinthine layer morphogenesis | response to peptide | reproduction | negative regulation of tyrosine phosphorylation of STAT protein | cardiovascular system development | response to temperature stimulus | response to molecule of bacterial origin | negative regulation of metabolic process | protein modification process | embryo development | macromolecule modification | embryonic placenta development | blood vessel development | response to nitrogen compound | response to external biotic stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | regulation of phosphorylation | response to ketone | response to lipid | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | placenta blood vessel development | negative regulation of insulin receptor signaling pathway | response to corticosteroid | positive regulation of cell differentiation | cellular response to cytokine stimulus | cell differentiation involved in embryonic placenta development | labyrinthine layer development | regulation of cellular protein metabolic process | response to gamma radiation | response to bacterium | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | embryonic morphogenesis | protein metabolic process | regulation of growth | response to organic substance | protein ubiquitination | tissue morphogenesis | regulation of JAK-STAT cascade | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | response to insulin | anatomical structure development | metabolic process | negative regulation of programmed cell death | embryonic organ development | organic substance metabolic process | animal organ development | regulation of insulin receptor signaling pathway | negative regulation of cellular protein metabolic process | response to heat | protein modification by small protein conjugation or removal | regulation of cellular response to insulin stimulus | regulation of phosphate metabolic process | morphogenesis of a branching epithelium | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | cellular response to leukemia inhibitory factor | signaling | response to organic cyclic compound | negative regulation of peptidyl-tyrosine phosphorylation | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | response to biotic stimulus | reproductive structure development | regulation of developmental process | developmental process | regulation of cell growth | cellular protein modification process | response to organonitrogen compound | embryonic placenta morphogenesis | in utero embryonic development | cellular metabolic process | placenta development | cellular response to organic substance | regulation of cell death | response to steroid hormone | spongiotrophoblast layer development | spongiotrophoblast differentiation | response to food | negative regulation of cell death | circulatory system development | regulation of inflammatory response | aging | regulation of cellular component organization | response to ionizing radiation | response to other organism | signal transduction | regulation of signaling | animal organ regeneration | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

cell | cytoplasm | intracellular